Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 16/20 | 0.73 |
| ▸ | PDE10A | Q9Y233 | 3/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13792321 | 0.84 | DPP4 (1.00) | DPP4PDE10A | |
| Hydrochloric Acid SCHEMBL29356163 | 0.83 | DPP4 (1.00) | DPP4PDE10A | |
| SCHEMBL4803200 | 0.81 | DPP4 (0.52) | DPP4PDE10AHSD17B10 | |
| SCHEMBL3360544 | 0.80 | DPP4 (0.61) | DPP4PDE10A | |
| SCHEMBL3360594 | 0.80 | DPP4 (0.71) | DPP4 | |
| SCHEMBL4814360 | 0.80 | DPP4 (0.48) | DPP4PDE10AHSD17B10 | |
| Hydrochloric Acid SCHEMBL3369616 | 0.80 | DPP4 (0.62) | DPP4PDE10A | |
| SCHEMBL3362127 | 0.79 | DPP4 (0.60) | DPP4 | |
| SCHEMBL8289766 | 0.79 | DPP4 (0.59) | DPP4 | |
| Hydrochloric Acid SCHEMBL3361829 | 0.79 | DPP4 (0.61) | DPP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7732446-B1 | Dipeptidyl peptidase inhibitors | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-06-08 | — | — | US | disclosed |
| US-7732446-B1 | Dipeptidyl peptidase inhibitors | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-06-08 | — | — | US | disclosed |