Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 5/20 | 0.59 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.59 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.59 |
| ▸ | MAOA | P21397 | 1/20 | 0.59 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.59 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.59 |
| ▸ | HTR2B | P41595 | 1/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | CRHBP | P24387 | 1/20 | 0.50 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.50 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.42 |
| ▸ | ESR1 | P03372 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | ACHE | P22303 | 2/20 | 0.37 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL83132 | 0.86 | CYP3A4 (0.58) | CYP3A4CHRM1ALOX15MAOATBXA2R | |
| Ammonia Solution, Strong SCHEMBL10706299 | 0.83 | CYP3A4 (0.55) | CYP3A4CHRM1ALOX15MAOATBXA2R | |
| SCHEMBL253926 | 0.80 | CYP3A4 (0.58) | CYP3A4CHRM1ALOX15MAOATBXA2R | |
| SCHEMBL3788864 | 0.79 | CYP3A4 (0.59) | CYP3A4CHRM1ALOX15MAOATBXA2R | |
| SCHEMBL7786855 | 0.79 | CYP3A4 (0.50) | CYP3A4CHRM1ALOX15MAOATBXA2R | |
| SCHEMBL6800963 | 0.79 | CYP3A4 (0.75) | CYP3A4CHRM1ALOX15MAOATBXA2R | |
| Methane SCHEMBL27301821 | 0.77 | CYP3A4 (0.55) | CYP3A4CHRM1ALOX15MAOATBXA2R | |
| SCHEMBL3785424 | 0.75 | CYP3A4 (0.54) | CYP3A4CHRM1ALOX15MAOATBXA2R | |
| SCHEMBL22265086 | 0.75 | CYP3A4 (0.46) | CYP3A4CHRM1ALOX15MAOATBXA2R | |
| SCHEMBL5249009 | 0.75 | CYP3A4 (0.54) | CYP3A4CHRM1ALOX15MAOATBXA2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 66 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103156800-A | Antibacterial and washing-free hand-cleaning liquid | ZHANG GUIPING | 2013-06-19 | — | — | CN | claimed |
| WO-2022083569-A1 | HETEROCYCLIC SPIRO COMPOUNDS AND METHODS OF USE | AMGEN INC. (US) | 2022-04-28 | — | — | WO | disclosed |
| CN-103156800-A | Antibacterial and washing-free hand-cleaning liquid | ZHANG GUIPING | 2013-06-19 | — | — | CN | disclosed |
| US-8338412-B2 | Inhibitors of P38 | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2012-12-25 | — | — | US | disclosed |
| US-20110281878-A1 | INHIBITORS OF p38 | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2011-11-17 | — | — | US | disclosed |
| US-20110160163-A1 | INHIBITORS OF p38 | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2011-06-30 | — | — | US | disclosed |
| WO-2011056589-A1 | BISPHOSPHONATE COMPOUNDS FOR TREATING BONE METABOLISM DISORDERS | WARNER CHILCOTT COMPANY, LLC (US) | 2011-05-12 | — | — | WO | disclosed |
| US-7919513-B2 | Inhibitors of p38 | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2011-04-05 | — | — | US | disclosed |
| US-6337375-B1 | RESIN WITH COLOR AND FLUORESCING AGENT | INTERNATIONAL BUSINESS MACHINES CORPORATION | 2002-01-08 | — | — | US | disclosed |
| EP-1145083-A2 | HYBRID SURFACE MODIFICATION PROCESS AND ARTICLE | BMC Industries, Inc. (US) | 2001-10-17 | — | — | EP | disclosed |
| US-4410738-A | Preparation of meta-chlorophenols by selective hydrodechlorination of polychlorophenols | RHONE-POULENC INDUSTRIES (FR) | 1983-10-18 | — | — | US | disclosed |
| US-4390675-A | EPOXYFULVENE, ACID CATALYST | ASHLAND OIL, INC. (US) | 1983-06-28 | — | — | US | disclosed |
| EP-0037353-B1 | PROCESS FOR THE ETHERIFICATION OF PHENOLS | RHONE-POULENC SPECIALITES CHIMIQUES (FR) | 1983-06-08 | — | — | EP | disclosed |
| EP-0076221-A1 | Process for the etherification of phenols | RHONE-POULENC SPECIALITES CHIMIQUES (FR) | 1983-04-06 | — | — | EP | disclosed |
| EP-0053280-A1 | Sealing composition, method for preparing said composition, integrated circuit module sealed therewith, and process for sealing | International Business Machines Corporation (US) | 1982-06-09 | — | — | EP | disclosed |
| EP-0009190-B1 | CURABLE COMPOSITION USEFUL FOR SCREEN-PRINTING, A CURED COATING COMPRISING SAID COMPOSITION AND PROCESS FOR SOLDERING PRINTED CIRCUIT BOARDS USING SAID COMPOSITION | International Business Machines Corporation (US) | 1982-04-28 | — | — | EP | disclosed |
| EP-0046719-A1 | Process for the etherification of phenols | RHONE-POULENC INDUSTRIES (FR) | 1982-03-03 | — | — | EP | disclosed |
| EP-0037353-A1 | Process for the etherification of phenols | RHONE-POULENC SPECIALITES CHIMIQUES (FR) | 1981-10-07 | — | — | EP | disclosed |
| US-4292230-A | Screen-printing composition and use thereof | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 1981-09-29 | — | — | US | disclosed |
| EP-0009190-A1 | Curable composition useful for screen-printing, a cured coating comprising said composition and process for soldering printed circuit boards using said composition | International Business Machines Corporation (US) | 1980-04-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110160163-A1 | INHIBITORS OF p38 | ZAP70, MAPK1, MAP3K20 | CYP3A4 4862/4885CHRM1 4627/4885ALOX15 2796/4885 |
| US-20110281878-A1 | INHIBITORS OF p38 | MAPK1, MAPK3, MAP3K1 | CYP3A4 4859/4885CHRM1 4684/4885ALOX15 2557/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.