Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 3/20 | 0.82 |
| ▸ | MAPT | P10636 | 5/20 | 0.76 |
| ▸ | APP | P05067 | 3/20 | 0.76 |
| ▸ | NFE2L2 | Q16236 | 4/20 | 0.73 |
| ▸ | BCHE | P06276 | 1/20 | 0.61 |
| ▸ | TLR2 | O60603 | 1/20 | 0.60 |
| ▸ | ERN1 | O75460 | 1/20 | 0.60 |
| ▸ | TLR1 | Q15399 | 1/20 | 0.60 |
| ▸ | TLR6 | Q9Y2C9 | 1/20 | 0.60 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.58 |
| ▸ | TXNRD3 | Q86VQ6 | 1/20 | 0.58 |
| ▸ | TXNRD2 | Q9NNW7 | 1/20 | 0.58 |
| ▸ | POLB | P06746 | 2/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | NPC1 | O15118 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | RECQL | P46063 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7724020 | 1.00 | BACE1 (0.82) | BACE1MAPTAPPNFE2L2BCHE | |
| SCHEMBL3218716 | 0.90 | BACE1 (1.00) | BACE1MAPTAPPNFE2L2MEN1 | |
| SCHEMBL3218734 | 0.90 | BACE1 (1.00) | BACE1MAPTAPPNFE2L2MEN1 | |
| SCHEMBL3842254 | 0.89 | BACE1 (0.67) | BACE1MAPTAPPNFE2L2BCHE | |
| SCHEMBL3842253 | 0.89 | BACE1 (0.67) | BACE1MAPTAPPNFE2L2BCHE | |
| SCHEMBL3218784 | 0.87 | MAPT (0.82) | BACE1MAPTAPPNFE2L2TXNRD1 | |
| SCHEMBL3216476 | 0.87 | APP (1.00) | BACE1MAPTAPPNFE2L2TXNRD1 | |
| SCHEMBL3218798 | 0.87 | MAPT (0.82) | BACE1MAPTAPPNFE2L2TXNRD1 | |
| SCHEMBL3216492 | 0.87 | APP (1.00) | BACE1MAPTAPPNFE2L2TXNRD1 | |
| SCHEMBL3687134 | 0.85 | KDM4E (0.66) | BACE1MAPTAPPNFE2L2BCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013054267-A1 | SYNERGISTIC COMPOSITION FOR PREVENTING AND TREATING DISORDERS CONNECTED WITH AGEING | MEDESTEA BIOTECH S.P.A. (IT) | 2013-04-18 | — | — | WO | disclosed |
| US-6395449-B1 | MIXTURE CONTAINING POLYGLUTARIMIDE AND SOLVENT | MICROCHEM CORP. | 2002-05-28 | — | — | US | disclosed |