Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 7/20 | 0.42 |
| ▸ | PDE4A | P27815 | 14/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | SSTR5 | P35346 | 1/20 | 0.39 |
| ▸ | PDE4C | Q08493 | 4/20 | 0.37 |
| ▸ | PDE4D | Q08499 | 4/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7733891 | 0.93 | PDE4A (0.40) | PDE4BPDE4ARECQLSSTR5PDE4C | |
| SCHEMBL7733871 | 0.88 | RECQL (0.41) | PDE4BPDE4ARECQLSSTR5PDE4C | |
| SCHEMBL3615395 | 0.85 | PDE4B (0.46) | PDE4BPDE4ASSTR5PDE4CPDE4D | |
| Carbamic Acid SCHEMBL7735372 | 0.84 | PDE4A (0.40) | PDE4BPDE4ARECQLPDE4CPDE4D | |
| SCHEMBL7735218 | 0.83 | PDE4A (0.42) | PDE4BPDE4ASSTR5PDE4CPDE4D | |
| SCHEMBL7734786 | 0.83 | PDE4B (0.41) | PDE4BPDE4ARECQLSSTR5PDE4C | |
| SCHEMBL7734102 | 0.81 | TSHR (0.43) | — | |
| SCHEMBL7724846 | 0.81 | PDE4A (0.45) | PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL7735374 | 0.80 | PDE4B (0.39) | PDE4BPDE4ASSTR5PDE4CPDE4D | |
| SCHEMBL7733932 | 0.79 | PDE4A (0.42) | PDE4BPDE4APDE4CPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6372770-B1 | TREATING A MAMMAL SUFFERING FROM A DISEASE STATE SELECTED FROM THE GROUP CONSISTING OF ASTHMA, ALLERGIES, INFLAMMATION, DEPRESSION, DEMENTIA, ATOPIC DISEASES, RHINITIS AND DISEASE STATES ASSOCIATED WITH ABNORMALLY HIGH PHYSIOLOGICAL LEVELS OF | EURO-CELTIQUE, S.A. | 2002-04-16 | — | — | US | claimed |