Sugi Predict

Sugi Predict / Compounds / SCHEMBL7726480

SCHEMBL7726480

SCHEMBL7726480

CCOC(=O)COC1C(O)[C@@H](COC(c2ccccc2)(c2ccc(OC)cc2)c2ccc(OC)cc2)O[C@H]1n1ccc(NC(=O)c2ccccc2)nc1=O

nearest known ligand 0.49

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
▸ P2RY6 Q15077 7/20 0.49
▸ P2RY14 Q15391 2/20 0.49
▸ NT5E P21589 1/20 0.49
▸ TYMP P19971 8/20 0.45
▸ POLB P06746 1/20 0.40
▸ ABL1 P00519 1/20 0.39
▸ RIN1 Q13671 1/20 0.39
▸ P2RY2 P41231 4/20 0.38
▸ P2RY4 P51582 3/20 0.38
▸ ST6GAL1 P15907 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6366294 1.00 P2RY6 (0.49) P2RY6P2RY14NT5ETYMPPOLB
SCHEMBL6932433 0.91 P2RY6 (0.52) P2RY6P2RY14NT5ETYMPPOLB
SCHEMBL6928957 0.89 P2RY6 (0.55) P2RY6P2RY14NT5ETYMPPOLB
SCHEMBL6930742 0.89 P2RY6 (0.51) P2RY6P2RY14NT5ETYMPPOLB
SCHEMBL6932379 0.88 P2RY6 (0.50) P2RY6P2RY14NT5ETYMPPOLB
SCHEMBL3454561 0.86 P2RY6 (0.52) P2RY6P2RY14NT5ETYMPPOLB
SCHEMBL7268016 0.85 P2RY6 (0.52) P2RY6P2RY14NT5ETYMPPOLB
SCHEMBL31485531 0.85 P2RY6 (0.55) P2RY6P2RY14NT5ETYMPPOLB
SCHEMBL6365464 0.85 P2RY6 (0.54) P2RY6P2RY14NT5EPOLBABL1
SCHEMBL7726491 0.85 P2RY6 (0.54) P2RY6P2RY14NT5EPOLBABL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6476205-B1 2′ Modified oligonucleotides ISIS PHARMACEUTICALS, INC. 2002-11-05 — — US disclosed