Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | C1S | P09871 | 13/20 | 0.77 |
| ▸ | PLAU | P00749 | 11/20 | 0.77 |
| ▸ | PLG | P00747 | 3/20 | 0.70 |
| ▸ | PLAT | P00750 | 3/20 | 0.70 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.70 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7475540 | 0.99 | C1S (0.75) | C1SPLAUPLGPLATPRSS1 | |
| SCHEMBL7736124 | 0.89 | C1S (0.81) | C1SPLAUPLGPLATPRSS1 | |
| Hydrochloric Acid SCHEMBL7473766 | 0.88 | C1S (0.80) | C1SPLAUPLGPLATPRSS1 | |
| SCHEMBL6924682 | 0.87 | C1S (1.00) | C1SPLAUPLGPLATPRSS1 | |
| SCHEMBL7736160 | 0.86 | C1S (0.79) | C1SPLAUPLGPLATPRSS1 | |
| SCHEMBL7736658 | 0.85 | C1S (0.83) | C1SPLAUPLGPLATPRSS1 | |
| SCHEMBL6926657 | 0.85 | C1S (1.00) | C1SPLAUPLGPLATPRSS1 | |
| Hydrochloric Acid SCHEMBL7466736 | 0.85 | C1S (0.77) | C1SPLAUPLGPLATPRSS1 | |
| SCHEMBL7727193 | 0.85 | C1S (0.69) | C1SPLAUPLGPLATPRSS1 | |
| SCHEMBL6924361 | 0.85 | C1S (1.00) | C1SPLAUPLGPLATPRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6403633-B2 | USEFUL ANTIANGIOGENIC, ANTIARTHRITIC, ANTIINFLAMMATORY, ANTIRESTENOTIC, ANTIINVASIVE, ANTIMETASTIC, ANTIOSTEOPOROTIC, ANTIRETINOPATHIC, CONTRACEPTIVE AND TUMORISTATIC TREATMENT AGENTS | 3-DIMENSIONAL PHARMACEUTICALS, INC. | 2002-06-11 | — | — | US | claimed |