Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.62 |
| ▸ | POLB | P06746 | 3/20 | 0.58 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.58 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.51 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | HTRA1 | Q92743 | 1/20 | 0.46 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.45 |
| ▸ | FNTA | P49354 | 1/20 | 0.44 |
| ▸ | FNTB | P49356 | 1/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7728020 | 1.00 | MEN1 (0.62) | MEN1KMT2APOLBCYP2C19CYP1A2 | |
| SCHEMBL7728781 | 1.00 | MEN1 (0.62) | MEN1KMT2APOLBCYP2C19CYP1A2 | |
| SCHEMBL1375463 | 0.91 | CYP3A4 (0.57) | MEN1KMT2APOLBCYP2C19CYP1A2 | |
| SCHEMBL1375465 | 0.91 | CYP3A4 (0.57) | MEN1KMT2APOLBCYP2C19CYP1A2 | |
| SCHEMBL7728565 | 0.91 | MEN1 (0.51) | MEN1KMT2APOLBCYP2C19CYP1A2 | |
| SCHEMBL7728568 | 0.91 | MEN1 (0.51) | MEN1KMT2APOLBCYP2C19CYP1A2 | |
| SCHEMBL7729359 | 0.86 | SMN1; SMN2 (0.49) | MEN1KMT2APOLBCYP2C19CYP1A2 | |
| SCHEMBL7729361 | 0.86 | SMN1; SMN2 (0.49) | MEN1KMT2APOLBCYP2C19CYP1A2 | |
| SCHEMBL13325458 | 0.86 | POLB (0.61) | MEN1KMT2APOLBCYP2C19CYP1A2 | |
| SCHEMBL7727705 | 0.85 | NPC1 (0.46) | MEN1KMT2APOLBCYP2C19CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6399629-B1 | PYRROLIDINES AND PIPERIDINES FOR TREATING MICROBIAL INFECTIONS BY REDUCING EXPORT OF COADMINISTERED ANTIMICROBIAL AGENT OR COMPOUND SYNTHESIZED BY MICROBES FOR THEIR GROWTH; REDUCING IN VIVO AVAILABILITY | MICROCIDE PHARMACEUTICALS, INC. | 2002-06-04 | — | — | US | disclosed |