Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SPHK1 | Q9NYA1 | 6/20 | 0.54 |
| ▸ | MAPT | P10636 | 5/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 5/20 | 0.54 |
| ▸ | SPHK2 | Q9NRA0 | 5/20 | 0.54 |
| ▸ | MEN1 | O00255 | 4/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.54 |
| ▸ | CETP | P11597 | 4/20 | 0.54 |
| ▸ | GMNN | O75496 | 3/20 | 0.54 |
| ▸ | LMNA | P02545 | 3/20 | 0.54 |
| ▸ | POLB | P06746 | 3/20 | 0.54 |
| ▸ | BLM | P54132 | 3/20 | 0.54 |
| ▸ | UBE2N | P61088 | 3/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.54 |
| ▸ | TP53 | P04637 | 3/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.54 |
| ▸ | GLA | P06280 | 2/20 | 0.54 |
| ▸ | THRB | P10828 | 2/20 | 0.54 |
| ▸ | CXCR5 | P32302 | 2/20 | 0.54 |
| ▸ | CCR6 | P51684 | 2/20 | 0.54 |
| ▸ | THPO | P40225 | 2/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13571254 | 1.00 | SPHK1 (0.54) | SPHK1MAPTCYP2D6SPHK2MEN1 | |
| SCHEMBL13571503 | 1.00 | SPHK1 (0.54) | SPHK1MAPTCYP2D6SPHK2MEN1 | |
| SCHEMBL13571253 | 1.00 | SPHK1 (0.54) | SPHK1MAPTCYP2D6SPHK2MEN1 | |
| SCHEMBL13571502 | 1.00 | SPHK1 (0.54) | SPHK1MAPTCYP2D6SPHK2MEN1 | |
| SCHEMBL13571233 | 0.87 | MAPT (0.44) | SPHK1MAPTCYP2D6SPHK2MEN1 | |
| SCHEMBL13571234 | 0.87 | MAPT (0.44) | SPHK1MAPTCYP2D6SPHK2MEN1 | |
| SCHEMBL13571166 | 0.87 | MAPT (0.44) | SPHK1MAPTCYP2D6SPHK2MEN1 | |
| SCHEMBL13571165 | 0.87 | MAPT (0.44) | SPHK1MAPTCYP2D6SPHK2MEN1 | |
| SCHEMBL1134639 | 0.83 | SPHK1 (0.54) | SPHK1MAPTCYP2D6SPHK2MEN1 | |
| SCHEMBL13685823 | 0.83 | SPHK1 (0.54) | SPHK1MAPTCYP2D6SPHK2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012150292-A1 | STEREOSELECTIVE SYNTHESIS OF CIS-4-METHYLSPHINGOSINE AND DERIVATIVES THEREOF | HUMBOLDT-UNIVERSITÄT ZU BERLIN (DE) | 2012-11-08 | — | — | WO | disclosed |
| EP-2520565-A1 | Stereoselective Synthesis of cis-4-Methylsphingosin | Humboldt Universität zu Berlin (DE) | 2012-11-07 | — | — | EP | disclosed |
| EP-2520565-A1 | Stereoselective Synthesis of cis-4-Methylsphingosin | Humboldt Universität zu Berlin (DE) | 2012-11-07 | — | — | EP | disclosed |
| EP-2520565-A1 | Stereoselective Synthesis of cis-4-Methylsphingosin | Humboldt Universität zu Berlin (DE) | 2012-11-07 | — | — | EP | disclosed |
| US-20020142982-A1 | Method for regulating angiogenesis | CONNECTICUT, THE UNIVERSITY OF | 2002-10-03 | — | — | US | disclosed |
| WO-2002017899-A2 | REGULATION OF ANGIOGENESIS VIA MODULATION OF EDG RECEPTOR MEDIATED SIGNAL TRANSDUCTION COMPRISING SPHINGOSINE-1-PHOSPHATE ADMINISTRATION | UNIVERSITY OF CONNECTICUT (US) | 2002-03-07 | — | — | WO | disclosed |