Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 6/20 | 0.39 |
| ▸ | MASP2 | O00187 | 1/20 | 0.37 |
| ▸ | F11 | P03951 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.36 |
| ▸ | KLKB1 | P03952 | 2/20 | 0.36 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.36 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.36 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.36 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.36 |
| ▸ | PLG | P00747 | 1/20 | 0.35 |
| ▸ | PLAU | P00749 | 1/20 | 0.35 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.35 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.35 |
| ▸ | BDKRB2 | P30411 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7731285 | 1.00 | F2 (0.39) | F2MASP2F11HDAC1KLKB1 | |
| SCHEMBL21523181 | 1.00 | F2 (0.39) | F2MASP2F11HDAC1KLKB1 | |
| SCHEMBL7731268 | 1.00 | F2 (0.39) | F2MASP2F11HDAC1KLKB1 | |
| SCHEMBL21436222 | 1.00 | F2 (0.39) | F2MASP2F11HDAC1KLKB1 | |
| SCHEMBL21436291 | 0.92 | KDM4E (0.43) | F2MASP2F11HDAC1SCN9A | |
| SCHEMBL21523166 | 0.92 | KDM4E (0.43) | F2MASP2F11HDAC1SCN9A | |
| SCHEMBL7728632 | 0.92 | KDM4E (0.43) | F2MASP2F11HDAC1SCN9A | |
| SCHEMBL1245431 | 0.92 | KDM4E (0.43) | F2MASP2F11HDAC1SCN9A | |
| SCHEMBL1246412 | 0.92 | KDM4E (0.43) | F2MASP2F11HDAC1SCN9A | |
| SCHEMBL7731762 | 0.91 | F2 (0.40) | F2MASP2F11HDAC1KLKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6399629-B1 | PYRROLIDINES AND PIPERIDINES FOR TREATING MICROBIAL INFECTIONS BY REDUCING EXPORT OF COADMINISTERED ANTIMICROBIAL AGENT OR COMPOUND SYNTHESIZED BY MICROBES FOR THEIR GROWTH; REDUCING IN VIVO AVAILABILITY | MICROCIDE PHARMACEUTICALS, INC. | 2002-06-04 | — | — | US | disclosed |