Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 10/20 | 0.46 |
| ▸ | RARA | P10276 | 3/20 | 0.46 |
| ▸ | RARG | P13631 | 1/20 | 0.46 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.40 |
| ▸ | PPARD | Q03181 | 1/20 | 0.36 |
| ▸ | PPARA | Q07869 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | MTOR | P42345 | 1/20 | 0.34 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | CASP1 | P29466 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7730600 | 0.97 | RARB (0.41) | RARBRARARARGS1PR1PPARD | |
| SCHEMBL12623035 | 0.95 | RARB (0.42) | RARBRARARARGS1PR1PPARD | |
| SCHEMBL12624814 | 0.95 | RARB (0.44) | RARBRARARARGS1PR1PPARD | |
| SCHEMBL12623046 | 0.92 | RARB (0.40) | RARBRARARARGS1PR1PPARD | |
| SCHEMBL7731405 | 0.92 | S1PR1 (0.38) | RARBRARARARGS1PR1PPARD | |
| SCHEMBL7735441 | 0.92 | SLC7A5 (0.38) | RARBRARARARGS1PR1PPARA | |
| SCHEMBL12625571 | 0.92 | RARB (0.43) | RARBRARARARGS1PR1PPARD | |
| SCHEMBL12625570 | 0.92 | RARB (0.43) | RARBRARARARGS1PR1PPARD | |
| SCHEMBL12625564 | 0.91 | RARB (0.43) | RARBRARARARGS1PR1PPARD | |
| SCHEMBL12623045 | 0.91 | RARB (0.43) | RARBRARARARGS1PR1PPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0786445-B1 | DIFLUOROXYMETHANE DERIVATIVE AND LIQUID CRYSTAL COMPOSITION | CHISSO CORP (JP) | 2002-07-17 | — | — | EP | disclosed |
| EP-0786445-A1 | DIFLUOROXYMETHANE DERIVATIVE AND LIQUID CRYSTAL COMPOSITION | CHISSO CORPORATION (JP) | 1997-07-30 | — | — | EP | disclosed |