Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.62 |
| ▸ | HTT | P42858 | 1/20 | 0.62 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7738714 | 0.85 | MAPT (0.62) | MAPTHTTTP53 | |
| SCHEMBL7738159 | 0.85 | MAPT (0.62) | MAPTHTTTP53 | |
| SCHEMBL8208474 | 0.82 | MAPT (0.58) | MAPTHTTTP53 | |
| SCHEMBL4082607 | 0.77 | MAPT (0.68) | MAPTHTTTP53 | |
| SCHEMBL21221877 | 0.77 | MAPT (0.68) | MAPTHTTTP53 | |
| SCHEMBL21221817 | 0.76 | MAPT (0.54) | MAPTHTT | |
| SCHEMBL7731984 | 0.73 | MAPT (0.62) | MAPTHTTTP53 | |
| SCHEMBL15294480 | 0.73 | MAPT (0.58) | MAPTHTTTP53 | |
| SCHEMBL21221793 | 0.72 | MAPT (0.61) | MAPTHTTTP53 | |
| SCHEMBL7738725 | 0.72 | MAPT (0.57) | MAPTHTTTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6417180-B1 | POLYMERASE ACTIVE SITE BINDING | UNIVERSITY OF MASSACHUSETTS | 2002-07-09 | — | — | US | disclosed |