Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MIF | P14174 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | OGG1 | O15527 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | KIF11 | P52732 | 1/20 | 0.37 |
| ▸ | FPR2 | P25090 | 1/20 | 0.37 |
| ▸ | CES2 | O00748 | 1/20 | 0.36 |
| ▸ | CES1 | P23141 | 1/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.36 |
| ▸ | MME | P08473 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1138666 | 0.84 | MIF (0.42) | MIFMEN1CYP1A2KMT2ACYP2C19 | |
| SCHEMBL6539846 | 0.84 | ESR1 (0.47) | MIFMEN1CYP1A2KMT2ACYP2C19 | |
| SCHEMBL830225 | 0.84 | MIF (0.59) | MIFMEN1CYP1A2KMT2ACYP2C19 | |
| SCHEMBL2298437 | 0.84 | CYP2C19 (0.55) | MIFMEN1CYP1A2KMT2ACYP2C19 | |
| SCHEMBL1143912 | 0.84 | CYP2C19 (0.55) | MIFMEN1CYP1A2KMT2ACYP2C19 | |
| SCHEMBL1138684 | 0.84 | CYP2C19 (0.55) | MIFMEN1CYP1A2KMT2ACYP2C19 | |
| Hydrochloric Acid SCHEMBL350882 | 0.82 | CYP2C19 (0.53) | MIFMEN1CYP1A2KMT2ACYP2C19 | |
| Hydrochloric Acid SCHEMBL1144491 | 0.82 | CYP2C19 (0.53) | MIFMEN1CYP1A2KMT2ACYP2C19 | |
| Hydrochloric Acid SCHEMBL8538776 | 0.82 | CYP2C19 (0.53) | MIFMEN1CYP1A2KMT2ACYP2C19 | |
| SCHEMBL24855930 | 0.81 | CYP2A6 (0.38) | MEN1CYP1A2KMT2AOGG1HDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6416861-B1 | COMBINATORIAL CHEMISTRY | NORTHWESTERN UNIVERSITY | 2002-07-09 | — | — | US | disclosed |
| WO-2000049022-A2 | ORGANOSILICON COMPOUNDS AND USES THEREOF | NORTHWESTERN UNIVERSITY (US) | 2000-08-24 | — | — | WO | disclosed |