Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLP1R | P43220 | 8/20 | 0.40 |
| ▸ | ANPEP | P15144 | 1/20 | 0.34 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.33 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.33 |
| ▸ | FAAH | O00519 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.31 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.31 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.31 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7721939 | 1.00 | GLP1R (0.40) | GLP1RANPEPSIRT6SIRT1FAAH | |
| SCHEMBL6233540 | 0.93 | GLP1R (0.45) | GLP1RSIRT6SIRT1FAAHFOLH1 | |
| SCHEMBL6233575 | 0.93 | GLP1R (0.45) | GLP1RSIRT6SIRT1FAAHFOLH1 | |
| SCHEMBL3485126 | 0.89 | GLP1R (0.45) | GLP1RSIRT6SIRT1FAAHMAPT | |
| SCHEMBL3485131 | 0.89 | GLP1R (0.45) | GLP1RSIRT6SIRT1FAAHMAPT | |
| SCHEMBL3484885 | 0.83 | GLP1R (0.54) | GLP1RSIRT6SIRT1 | |
| SCHEMBL4517738 | 0.83 | GLP1R (0.54) | GLP1RSIRT6SIRT1 | |
| SCHEMBL16326833 | 0.82 | GLP1R (0.53) | GLP1RSIRT6SIRT1 | |
| SCHEMBL16493149 | 0.79 | GLP1R (0.49) | GLP1RSIRT6SIRT1FOLH1TSHR | |
| SCHEMBL7758735 | 0.79 | GLP1R (0.45) | GLP1RFOLH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6403705-B1 | POLYPHENYENEVINYLENES FUNCTIONALIZED BY GROUPS WITH A VERY STRONG AFFINITY FOR BIOLOGICAL MACROMOLECULES; SPIRAL CRYSTALLIZATION | COMMISSARIAT A L'ENERGIE ATOMIQUE (FR) | 2002-06-11 | — | — | US | disclosed |