SCHEMBL7733716

SCHEMBL7733716

CN(C(=O)C(C)(C)C)c1ccc(N(C)C(=O)C(C)(C)C)cc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NOTUM Q6P988 1/20 0.52
KMT2A Q03164 4/20 0.45
SMN1; SMN2 Q16637 4/20 0.45
MEN1 O00255 3/20 0.45
CYP3A4 P08684 1/20 0.45
CYP2C9 P11712 1/20 0.45
CYP2C19 P33261 1/20 0.45
NPY2R P49146 1/20 0.41
MAPT P10636 3/20 0.39
ALDH1A1 P00352 3/20 0.39
HPGD P15428 1/20 0.39
NPSR1 Q6W5P4 3/20 0.38
KDM4E B2RXH2 1/20 0.38
GAA P10253 1/20 0.38
THRB P10828 1/20 0.38
TDP1 Q9NUW8 1/20 0.38
MLYCD O95822 1/20 0.38
NR1H4 Q96RI1 1/20 0.38
RAB9A P51151 2/20 0.37
CNR2 P34972 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15539862 0.89 NOTUM (0.49) NOTUMKMT2ASMN1; SMN2MEN1CYP3A4
SCHEMBL15540001 0.89 NOTUM (0.45) NOTUMKMT2ASMN1; SMN2MEN1CYP3A4
SCHEMBL31222337 0.89 NOTUM (0.49) NOTUMKMT2ASMN1; SMN2MEN1CYP3A4
SCHEMBL21653748 0.89 NOTUM (0.45) NOTUMKMT2ASMN1; SMN2MEN1CYP3A4
SCHEMBL8946139 0.89 KMT2A (0.60) NOTUMKMT2ASMN1; SMN2MEN1CYP3A4
Water SCHEMBL11236248 0.88 NOTUM (0.44) NOTUMKMT2ASMN1; SMN2MEN1CYP3A4
Water SCHEMBL11236243 0.88 NOTUM (0.44) NOTUMKMT2ASMN1; SMN2MEN1CYP3A4
SCHEMBL24340302 0.86 NOTUM (0.50) NOTUMKMT2ASMN1; SMN2MAPTALDH1A1
SCHEMBL15270371 0.84 NOTUM (0.41) NOTUMKMT2ASMN1; SMN2MEN1CYP3A4
SCHEMBL2578844 0.84 NOTUM (0.41) NOTUMKMT2ASMN1; SMN2MEN1CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6399272-B1 Phenylenediamine derivative-type additive useful for a chemically amplified photoresist HYUNDAI ELECTRONICS INDUSTRIES CO., LTD. (KR) 2002-06-04 US disclosed