Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR4 | O00206 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7697030 | 1.00 | TLR4 (0.50) | TLR4CYP2D6ALDH1A1KMT2AMAPT | |
| SCHEMBL929873 | 1.00 | TLR4 (0.50) | TLR4CYP2D6ALDH1A1KMT2AMAPT | |
| SCHEMBL3656801 | 1.00 | TLR4 (0.50) | TLR4CYP2D6ALDH1A1KMT2AMAPT | |
| SCHEMBL7392059 | 1.00 | TLR4 (0.50) | TLR4CYP2D6ALDH1A1KMT2AMAPT | |
| SCHEMBL10792572 | 1.00 | TLR4 (0.50) | TLR4CYP2D6ALDH1A1KMT2AMAPT | |
| SCHEMBL2470785 | 0.98 | TLR4 (0.51) | TLR4CYP2D6ALDH1A1KMT2AMAPT | |
| SCHEMBL276016 | 0.98 | TLR4 (0.51) | TLR4CYP2D6ALDH1A1KMT2AMAPT | |
| SCHEMBL28368812 | 0.97 | TLR4 (0.50) | TLR4CYP2D6ALDH1A1KMT2AMAPT | |
| SCHEMBL12606807 | 0.93 | TLR4 (0.52) | TLR4CYP2D6ALDH1A1KMT2AMAPT | |
| SCHEMBL321283 | 0.93 | TLR4 (0.52) | TLR4CYP2D6ALDH1A1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5876492-A | Ink compositions containing esters | XEROX CORPORATION (US) | 1999-03-02 | — | — | US | claimed |
| EP-1015479-A4 | COMBINATORIAL LIBRARIES OF PEPTIDOMIMETIC MACROCYCLES AND PROCESSES THEREFOR | LILLY CO ELI (US) | 2002-07-24 | — | — | EP | disclosed |
| EP-1015479-A1 | COMBINATORIAL LIBRARIES OF PEPTIDOMIMETIC MACROCYCLES AND PROCESSES THEREFOR | ELI LILLY AND COMPANY (US) | 2000-07-05 | — | — | EP | disclosed |
| EP-0973936-A1 | COMBINATORIAL LIBRARIES OF PEPTIDOMIMETIC AMINOTHIOETHER ACIDS | ELI LILLY AND COMPANY (US) | 2000-01-26 | — | — | EP | disclosed |
| EP-0903382-A1 | Semi-solid hot melt ink compositions containing esters | XEROX CORPORATION (US) | 1999-03-24 | — | — | EP | disclosed |
| US-5876492-A | Ink compositions containing esters | XEROX CORPORATION (US) | 1999-03-02 | — | — | US | disclosed |
| WO-1998046631-A1 | COMBINATORIAL LIBRARIES OF PEPTIDOMIMETIC MACROCYCLES AND PROCESSES THEREFOR | ELI LILLY AND COMPANY (US) | 1998-10-22 | — | — | WO | disclosed |
| WO-1998046786-A1 | COMBINATORIAL LIBRARIES OF PEPTIDOMIMETIC AMINOTHIOETHER ACIDS | ELI LILLY AND COMPANY (US) | 1998-10-22 | — | — | WO | disclosed |