Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.73 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.70 |
| ▸ | RARB | P10826 | 4/20 | 0.65 |
| ▸ | TP53 | P04637 | 1/20 | 0.65 |
| ▸ | TSHR | P16473 | 1/20 | 0.65 |
| ▸ | PLA2G4B | P0C869 | 6/20 | 0.63 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | THRA | P10827 | 1/20 | 0.55 |
| ▸ | THRB | P10828 | 1/20 | 0.55 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7738822 | 1.00 | GAA (0.73) | GAAL3MBTL1RARBTP53TSHR | |
| SCHEMBL7737425 | 1.00 | GAA (0.73) | GAAL3MBTL1RARBTP53TSHR | |
| SCHEMBL7737441 | 0.94 | RARB (0.74) | GAAL3MBTL1RARBTP53TSHR | |
| SCHEMBL2354201 | 0.92 | GAA (0.86) | GAAL3MBTL1RARBTP53TSHR | |
| SCHEMBL762326 | 0.92 | GAA (0.86) | GAAL3MBTL1RARBTP53TSHR | |
| SCHEMBL2035476 | 0.92 | GAA (0.86) | GAAL3MBTL1RARBTP53TSHR | |
| SCHEMBL10499017 | 0.92 | GAA (0.86) | GAAL3MBTL1RARBTP53TSHR | |
| SCHEMBL2039972 | 0.92 | GAA (0.86) | GAAL3MBTL1RARBTP53TSHR | |
| SCHEMBL2039230 | 0.92 | GAA (0.86) | GAAL3MBTL1RARBTP53TSHR | |
| SCHEMBL15177361 | 0.92 | GAA (0.86) | GAAL3MBTL1RARBTP53TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7790744-B2 | Cyclic peptide antifungal agents and process for preparation thereof | ELI LILLY AND COMPANY (US) | 2010-09-07 | — | — | US | disclosed |
| US-6743777-B1 | TRISPHENYL ACYL DERIVATIVES OF THE ECHINOCANDIN CLASS; CANDIDA ALBICANS; ANTIFUNGAL AND ANTIPARASITIC; CYCLIC HEXAPEPTIDES HAVING UNIQUE SIDE CHAIN ACYL GROUP | ELI LILLY AND COMPANY | 2004-06-01 | — | — | US | disclosed |