Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.31 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | DRD2 | P14416 | 1/20 | 0.31 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.31 |
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
| ▸ | HTR2C | P28335 | 1/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.31 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6363955 | 0.86 | GRM2 (0.34) | CYP2D6CYP2C9CYP2C19CYP3A4CYP2C8 | |
| SCHEMBL6367773 | 0.85 | CYP3A4 (0.33) | CYP2D6CYP2C9CYP2C19CYP3A4CYP2C8 | |
| SCHEMBL6362211 | 0.85 | GRM2 (0.36) | CYP2D6CYP2C9CYP2C19CYP3A4CYP2C8 | |
| SCHEMBL6363296 | 0.85 | GRM2 (0.36) | CYP2D6CYP2C9CYP2C19CYP3A4CYP2C8 | |
| SCHEMBL6362621 | 0.85 | GRM2 (0.36) | CYP2D6CYP2C9CYP2C19CYP3A4CYP2C8 | |
| SCHEMBL19582746 | 0.84 | SPHK1 (0.44) | CYP2C9GAAMAPTKMT2AMEN1 | |
| SCHEMBL6752073 | 0.84 | MAPT (0.34) | CYP2D6CYP2C9CYP2C19CYP3A4CYP2C8 | |
| SCHEMBL6367754 | 0.84 | MAPT (0.34) | CYP2D6CYP2C9CYP2C19CYP3A4CYP2C8 | |
| SCHEMBL6362663 | 0.84 | MAPT (0.34) | CYP2D6CYP2C9CYP2C19CYP3A4CYP2C8 | |
| SCHEMBL7733088 | 0.84 | MAPT (0.34) | CYP2D6CYP2C9CYP2C19CYP3A4CYP2C8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6476266-B1 | Diamino compound and production process for the same | CHISSO CORPORATION (JP) | 2002-11-05 | — | — | US | disclosed |