Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | ACP3 | P15309 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | ACHE | P22303 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | CES2 | O00748 | 1/20 | 0.42 |
| ▸ | CES1 | P23141 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11432821 | 0.80 | TSHR (0.61) | TSHRLMNAALDH1A1ACP3SMN1; SMN2 | |
| SCHEMBL384083 | 0.80 | TSHR (0.61) | TSHRLMNAALDH1A1ACP3SMN1; SMN2 | |
| SCHEMBL8870718 | 0.80 | KMT2A (0.54) | TSHRLMNAALDH1A1KDM4EACP3 | |
| SCHEMBL741878 | 0.80 | TSHR (0.52) | TSHRLMNAALDH1A1KDM4EACP3 | |
| SCHEMBL3845818 | 0.80 | KMT2A (0.54) | TSHRLMNAALDH1A1KDM4EACP3 | |
| SCHEMBL5757472 | 0.80 | TSHR (0.52) | TSHRLMNAALDH1A1KDM4EACP3 | |
| SCHEMBL12395375 | 0.80 | TSHR (0.52) | TSHRLMNAALDH1A1KDM4EACP3 | |
| SCHEMBL28757603 | 0.80 | TSHR (0.52) | TSHRLMNAALDH1A1KDM4EACP3 | |
| SCHEMBL7295540 | 0.78 | TSHR (0.48) | TSHRLMNAALDH1A1KDM4EACP3 | |
| SCHEMBL2540712 | 0.77 | TSHR (0.57) | TSHRLMNAALDH1A1ACP3SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6407083-B1 | ADMINISTERING AS 7-NITROBENZISOSELENAZOLINE DERIVATIVES AS ANTITUMOR AND ANTICARCINOGENIC AGENTS | OXIS INTERNATIONAL, INC. | 2002-06-18 | — | — | US | disclosed |
| US-6130212-A | ANTITUMOR | OXIS INTERNATIONAL S.A. (US) | 2000-10-10 | — | — | US | disclosed |
| US-6057310-A | TREATING LEUKEMIA, BREAST CANCER | OXIS ISLE OF MAN, LIMITED (US) | 2000-05-02 | — | — | US | disclosed |
| US-6001825-A | Use of novel organoselenium compounds as pro-oxidizing agents their methods of preparation and pharmaceutical compositions and application thereof | OXIS ISLE OF MAN, LIMITED (US) | 1999-12-14 | — | — | US | disclosed |
| EP-0819682-A1 | Use of novel organoselenium compounds as pro-oxidizing agents, their methods of preparation and pharmaceutical compositions and application containing them | Oxis International S.A. (FR) | 1998-01-21 | — | — | EP | disclosed |