⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL29493442 | 0.97 | — | — | |
| SCHEMBL11551941 | 0.95 | GAA (0.86) | — | |
| SCHEMBL11557391 | 0.95 | GAA (0.86) | — | |
| SCHEMBL11562571 | 0.95 | GAA (0.86) | — | |
| SCHEMBL11554085 | 0.95 | GAA (0.86) | — | |
| SCHEMBL9542421 | 0.92 | GAA (0.73) | — | |
| Morpholine SCHEMBL29053755 | 0.91 | GAA (0.71) | — | |
| SCHEMBL11581022 | 0.90 | GAA (0.77) | — | |
| SCHEMBL18873556 | 0.87 | GAA (0.72) | — | |
| SCHEMBL440870 | 0.84 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 3123 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4105216-B1 | DIHYDRONAPHTHYRIDINONE COMPOUND, AND PREPARATION METHOD THEREFOR AND MEDICAL USE THEREOF | GENFLEET THERAPEUTICS SHANGHAI INC (CN) | 2026-05-20 | — | — | EP | claimed |
| US-20260109697-A1 | 4-(IMIDAZO[1,2-A]PYRIDIN-3-YL)-PYRIMIDINE DERIVATIVES | MERCK PATENT GMBH (DE) | 2026-04-23 | — | — | US | claimed |
| EP-4724442-A1 | AGONISM-ANTAGONISM IN ENDOSOMAL TLRS BY MODULATING CHEMICAL FEATURES IN 8-OXOPURINE: PROCESS FOR PREPARATION AND APPLICATION THEREOF | Council of Scientific and Industrial Research (IN) | 2026-04-15 | — | — | EP | claimed |
| EP-4704830-A2 | MRGPRX2 INHIBITORS AND METHODS OF USE THEREOF | Septerna, Inc. (US) | 2026-03-11 | — | — | EP | claimed |
| EP-4103559-B1 | HETEROCYCLIC PAD4 INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2026-03-04 | — | — | EP | claimed |
| US-12565496-B2 | Substituted 1H-pyrrolo[3,2-b]pyridine compounds and methods of use thereof | BAYER AKTIENGESELLSCHAFT (DE) | 2026-03-03 | — | — | US | claimed |
| US-12486260-B2 | Indazolyl-isoxazole derivatives for the treatment of diseases such as cancer | MERCK PATENT GMBH (DE) | 2025-12-02 | — | — | US | claimed |
| US-12410194-B2 | Potent and selective azaindole inhibitors of CDK8 and CDK19 | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2025-09-09 | — | — | US | claimed |
| US-20250223285-A1 | NOVEL HETEROCYCLIC DERIVATIVES USEFUL AS SHP2 INHIBITORS | JACOBIO PHARMACEUTICALS CO LTD (CN) | 2025-07-10 | — | — | US | claimed |
| CN-120157629-A | Synthesis process of morpholone derivative | 北京颖诺凯胜科技有限公司 | 2025-06-17 | — | — | CN | claimed |
| US-5349045-A | Polymer derived from cyclic amide and medical devices manufactured therefrom | UNITED STATES SURGICAL CORPORATION (US) | 1994-09-20 | — | — | US | claimed |
| EP-0266950-B1 | Nor-statine and nor-cyclostatine polypeptides | PFIZER (US) | 1993-12-29 | — | — | EP | claimed |
| US-5211662-A | Bicomposite intraocular lenses | ALCON LABORATORIES, INC. (US) | 1993-05-18 | — | — | US | claimed |
| EP-0473337-A2 | Nor-statine and nor-cyclostatine polypeptides in the treatment of ocular hypertension and glaucoma | PFIZER INC. (US) | 1992-03-04 | — | — | EP | claimed |
| US-5034376-A | Nor-statine and nor-cyclostatine polypeptides | PFIZER INC. (US) | 1991-07-23 | — | — | US | claimed |
| US-4997442-A | Self-supporting eye implants; hydrogel; low water content; high strength, rigidity | ALCON LABORATORIES, INC. (US) | 1991-03-05 | — | — | US | claimed |
| EP-0266950-A2 | Nor-statine and nor-cyclostatine polypeptides | PFIZER INC. (US) | 1988-05-11 | — | — | EP | claimed |
| CN-87101499-A | Preparation method of n-statinib and n-cyclostatini polypeptide | — | 1988-05-11 | — | — | CN | claimed |
| EP-0258391-A1 | USE OF HETEROCYCLIC NITROGEN-CONTAINING COMPOUNDS FOR REDUCING MOISTURE LOSS FROM PLANTS AND INCREASING CROP YIELD | RHONE POULENC NEDERLAND B.V. (NL) | 1988-03-09 | — | — | EP | claimed |
| WO-1987004321-A2 | USE OF HETEROCYCLIC NITROGEN-CONTAINING COMPOUNDS FOR REDUCING MOISTURE LOSS FROM PLANTS AND INCREASING CROP YIELD | RHONE-POULENC NEDERLANDS B.V. (NL) | 1987-07-30 | — | — | WO | claimed |