Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 6/20 | 0.37 |
| ▸ | LRRK2 | Q5S007 | 6/20 | 0.35 |
| ▸ | BRD4 | O60885 | 1/20 | 0.35 |
| ▸ | SOAT1 | P35610 | 2/20 | 0.35 |
| ▸ | FPR1 | P21462 | 1/20 | 0.33 |
| ▸ | FPR2 | P25090 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7726344 | 0.86 | SOAT1 (0.35) | GRM2SOAT1ALDH1A1 | |
| SCHEMBL7736171 | 0.85 | GRM2 (0.39) | GRM2SOAT1 | |
| SCHEMBL7726027 | 0.82 | SOAT1 (0.36) | GRM2SOAT1ALDH1A1MAPT | |
| SCHEMBL7734588 | 0.78 | GRM2 (0.38) | GRM2SOAT1MAPTNPSR1 | |
| SCHEMBL7738006 | 0.78 | SOAT1 (0.39) | GRM2SOAT1POLBALDH1A1 | |
| SCHEMBL7738806 | 0.78 | GRM2 (0.38) | GRM2SOAT1ALDH1A1 | |
| SCHEMBL7734469 | 0.78 | SOAT1 (0.36) | GRM2SOAT1 | |
| SCHEMBL7735770 | 0.78 | SOAT1 (0.35) | GRM2SOAT1 | |
| SCHEMBL7735581 | 0.74 | LPAR1 (0.41) | GRM2LRRK2BRD4SOAT1 | |
| SCHEMBL7737837 | 0.73 | SOAT1 (0.35) | GRM2SOAT1MAPTNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6452008-B2 | 3-UREA COMPOUND FROM THE 3-AMIDO COMPOUND WITHOUT AZIDATION PROCESS WHICH HAS RISK OF EXPLOSION; REACTION WITH HYPOCHLORITE, HYPOBROMITE OR LEAD TETRAACETATE AND THEN AN AMINE; ACAT INHIBITOR | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 2002-09-17 | — | — | US | disclosed |
| US-6300500-B1 | Preparation of pyridone derivatives using phthalimido containing starting material | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 2001-10-09 | — | — | US | disclosed |
| EP-1086948-A1 | PYRIDONE DERIVATIVES AND PROCESS FOR PRODUCING THE SAME | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 2001-03-28 | — | — | EP | disclosed |