SCHEMBL7735406

SCHEMBL7735406

CCOC(C)Oc1ccc(PC(=O)c2c(Cl)cccc2Cl)cc1.COc1ccc(PC(=O)c2c(Cl)cccc2Cl)c(OC)c1.[LiH].[LiH]

nearest known ligand 0.35

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.35
FFAR1 O14842 1/20 0.35
ABCG2 Q9UNQ0 1/20 0.34
KMT2A Q03164 3/20 0.33
MEN1 O00255 2/20 0.33
ITGB1 P05556 2/20 0.33
ITGA4 P13612 2/20 0.33
PTGS2 P35354 1/20 0.33
ELANE P08246 3/20 0.33
SMN1; SMN2 Q16637 2/20 0.33
ALDH1A1 P00352 1/20 0.33
MAPT P10636 1/20 0.33
TOP1 P11387 1/20 0.32
TP53 P04637 1/20 0.32
EGFR P00533 1/20 0.32
FGFR1 P11362 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7189876 0.90 SMN1; SMN2 (0.37) LMNAFFAR1ITGB1ITGA4SMN1; SMN2
SCHEMBL7182533 0.89 FFAR1 (0.36) LMNAFFAR1ABCG2KMT2AITGB1
SCHEMBL7182468 0.88 FFAR1 (0.34) FFAR1KMT2AMEN1ELANEMAPT
SCHEMBL7178010 0.88 FFAR1 (0.34) LMNAFFAR1ALDH1A1MAPT
SCHEMBL7177839 0.85 KMT2A (0.41) ABCG2KMT2ASMN1; SMN2ALDH1A1TP53
SCHEMBL7181637 0.83 SMN1; SMN2 (0.40) FFAR1KMT2ASMN1; SMN2ALDH1A1MAPT
SCHEMBL7175310 0.83 ABCG2 (0.44) LMNAABCG2KMT2AMEN1PTGS2
SCHEMBL7187636 0.83 TRPM4 (0.32) LMNAFFAR1KMT2AMEN1ITGB1
SCHEMBL7175370 0.83 ITGB1 (0.34) LMNAFFAR1KMT2AMEN1ITGB1
SCHEMBL7187388 0.83 SMN1; SMN2 (0.38) LMNAFFAR1KMT2ASMN1; SMN2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6399805-B2 SUCH AS LITHIUM 2,6-DIMETHYLBENZOYLPHENYLPHOSPHINE, USE AS PHOTOINITIATORS IN PHOTOCURABLE COMPOSITIONS SUCH AS FOR PHOTOGRAPHIC PRODUCTION OF RELIEF IMAGES CIBA SPECIALTY CHEMICALS CORPORATION 2002-06-04 US disclosed