Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 1/20 | 0.53 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.53 |
| ▸ | PDE4A | P27815 | 14/20 | 0.52 |
| ▸ | PDE4D | Q08499 | 10/20 | 0.44 |
| ▸ | PDE4B | Q07343 | 9/20 | 0.44 |
| ▸ | PDE4C | Q08493 | 9/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | CETP | P11597 | 1/20 | 0.42 |
| ▸ | FPR2 | P25090 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7734126 | 0.87 | NPC1 (0.53) | KDM4ENPC1ALDH1A1HPGDRAB9A | |
| SCHEMBL7737479 | 0.81 | PDE4A (0.45) | S1PR1S1PR3PDE4APDE4DPDE4B | |
| SCHEMBL7733947 | 0.81 | PDE4A (0.43) | S1PR1S1PR3PDE4APDE4DPDE4B | |
| SCHEMBL3615395 | 0.81 | PDE4B (0.46) | S1PR1S1PR3PDE4APDE4DPDE4B | |
| SCHEMBL7403476 | 0.74 | PDE4A (0.57) | S1PR1S1PR3PDE4APDE4DPDE4B | |
| SCHEMBL14176200 | 0.72 | S1PR1 (0.71) | S1PR1S1PR3PDE4APDE4DPDE4B | |
| SCHEMBL8209414 | 0.72 | PDE4A (0.67) | PDE4APDE4DPDE4BPDE4CFPR2 | |
| SCHEMBL5823060 | 0.71 | PDE4A (0.77) | S1PR1S1PR3PDE4APDE4DPDE4B | |
| SCHEMBL8478398 | 0.69 | PDE4A (0.58) | PDE4APDE4DPDE4BPDE4C | |
| SCHEMBL8326223 | 0.69 | PDE4B (0.44) | PDE4APDE4DPDE4BPDE4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6372770-B1 | TREATING A MAMMAL SUFFERING FROM A DISEASE STATE SELECTED FROM THE GROUP CONSISTING OF ASTHMA, ALLERGIES, INFLAMMATION, DEPRESSION, DEMENTIA, ATOPIC DISEASES, RHINITIS AND DISEASE STATES ASSOCIATED WITH ABNORMALLY HIGH PHYSIOLOGICAL LEVELS OF | EURO-CELTIQUE, S.A. | 2002-04-16 | — | — | US | claimed |