Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.61 |
| ▸ | KCNQ2 | O43526 | 6/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.50 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.49 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.48 |
| ▸ | CSNK1D | P48730 | 2/20 | 0.47 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.47 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.47 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.47 |
| ▸ | CACNA1I | Q9P0X4 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | ANO1 | Q5XXA6 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1306728 | 0.77 | MEN1 (0.65) | MEN1KMT2AALDH1A1KCNQ2MAPK8 | |
| SCHEMBL6960412 | 0.76 | GAA (0.43) | MEN1KMT2AALDH1A1MAPTL3MBTL1 | |
| SCHEMBL6581781 | 0.76 | KCNQ2 (0.60) | MEN1KMT2AALDH1A1KCNQ2MAPT | |
| SCHEMBL4352857 | 0.76 | MEN1 (0.59) | MEN1KMT2AALDH1A1EPHX2L3MBTL1 | |
| SCHEMBL21156700 | 0.76 | MEN1 (0.65) | MEN1KMT2AALDH1A1KCNQ2MAPT | |
| SCHEMBL1309785 | 0.75 | MEN1 (0.64) | MEN1KMT2AALDH1A1KCNQ2MAPT | |
| SCHEMBL1669892 | 0.74 | MEN1 (0.63) | MEN1KMT2AALDH1A1MAPTMAPK8 | |
| SCHEMBL1669896 | 0.74 | MEN1 (0.63) | MEN1KMT2AALDH1A1MAPTMAPK8 | |
| SCHEMBL28623703 | 0.74 | CXCR2 (0.47) | MEN1KMT2AALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL15648896 | 0.73 | KMT2A (0.60) | MEN1KMT2AALDH1A1KCNQ2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6372770-B1 | TREATING A MAMMAL SUFFERING FROM A DISEASE STATE SELECTED FROM THE GROUP CONSISTING OF ASTHMA, ALLERGIES, INFLAMMATION, DEPRESSION, DEMENTIA, ATOPIC DISEASES, RHINITIS AND DISEASE STATES ASSOCIATED WITH ABNORMALLY HIGH PHYSIOLOGICAL LEVELS OF | EURO-CELTIQUE, S.A. | 2002-04-16 | — | — | US | disclosed |