Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 11/20 | 0.39 |
| ▸ | PDE4B | Q07343 | 8/20 | 0.38 |
| ▸ | PDE4D | Q08499 | 7/20 | 0.38 |
| ▸ | PDE4C | Q08493 | 6/20 | 0.38 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.37 |
| ▸ | TPH1 | P17752 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Carbamic Acid SCHEMBL7735701 | 1.00 | PDE4A (0.39) | PDE4APDE4BPDE4DPDE4CMAPK14 | |
| SCHEMBL7724881 | 0.96 | PDE4A (0.40) | PDE4APDE4BPDE4DPDE4C | |
| SCHEMBL7724878 | 0.96 | PDE4A (0.40) | PDE4APDE4BPDE4DPDE4C | |
| SCHEMBL7735698 | 0.91 | PDE4B (0.41) | PDE4APDE4BPDE4DPDE4CMAPK14 | |
| Carbamic Acid SCHEMBL7735372 | 0.88 | PDE4A (0.40) | PDE4APDE4BPDE4DPDE4C | |
| SCHEMBL7733965 | 0.88 | PDE4B (0.41) | PDE4APDE4BPDE4DPDE4C | |
| SCHEMBL7733932 | 0.87 | PDE4A (0.42) | PDE4APDE4BPDE4DPDE4C | |
| SCHEMBL7725341 | 0.87 | PDE4B (0.40) | PDE4APDE4BPDE4DPDE4C | |
| SCHEMBL7734722 | 0.86 | PDE4A (0.41) | PDE4APDE4BPDE4DPDE4C | |
| SCHEMBL7735374 | 0.84 | PDE4B (0.39) | PDE4APDE4BPDE4DPDE4CMAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6372770-B1 | TREATING A MAMMAL SUFFERING FROM A DISEASE STATE SELECTED FROM THE GROUP CONSISTING OF ASTHMA, ALLERGIES, INFLAMMATION, DEPRESSION, DEMENTIA, ATOPIC DISEASES, RHINITIS AND DISEASE STATES ASSOCIATED WITH ABNORMALLY HIGH PHYSIOLOGICAL LEVELS OF | EURO-CELTIQUE, S.A. | 2002-04-16 | — | — | US | claimed |