Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | C1S | P09871 | 3/20 | 0.53 |
| ▸ | PLAU | P00749 | 3/20 | 0.49 |
| ▸ | NPC1 | O15118 | 6/20 | 0.49 |
| ▸ | RAB9A | P51151 | 6/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.48 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | CNR1 | P21554 | 1/20 | 0.44 |
| ▸ | CNR2 | P34972 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | CLK1 | P49759 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6924633 | 0.99 | C1S (0.52) | C1SPLAUNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL7359059 | 0.90 | C1S (0.53) | C1SPLAU | |
| SCHEMBL7736159 | 0.88 | C1S (0.55) | C1SPLAUHDAC3HDAC4HDAC1 | |
| Hydrochloric Acid SCHEMBL6924675 | 0.88 | C1S (0.52) | C1SPLAU | |
| Hydrochloric Acid SCHEMBL6922137 | 0.87 | C1S (0.54) | C1SPLAUHDAC3HDAC4HDAC1 | |
| SCHEMBL6926778 | 0.85 | NPC1 (0.56) | NPC1RAB9ASMN1; SMN2MAPTHDAC3 | |
| SCHEMBL7736168 | 0.82 | PLAU (0.49) | C1SPLAU | |
| SCHEMBL7736645 | 0.80 | C1S (0.55) | C1SPLAU | |
| SCHEMBL7735235 | 0.80 | PLAU (0.54) | C1SPLAUSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL6925651 | 0.79 | C1S (0.54) | C1SPLAU |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6403633-B2 | USEFUL ANTIANGIOGENIC, ANTIARTHRITIC, ANTIINFLAMMATORY, ANTIRESTENOTIC, ANTIINVASIVE, ANTIMETASTIC, ANTIOSTEOPOROTIC, ANTIRETINOPATHIC, CONTRACEPTIVE AND TUMORISTATIC TREATMENT AGENTS | 3-DIMENSIONAL PHARMACEUTICALS, INC. | 2002-06-11 | — | — | US | claimed |