SCHEMBL7736

SCHEMBL7736

C[C](F)F

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL80069 0.83
SCHEMBL28271866 0.77
SCHEMBL13423857 0.77
SCHEMBL726605 0.77
SCHEMBL727585 0.77
SCHEMBL7025707 0.77
Fluoromethane SCHEMBL8981607 0.73
SCHEMBL8225551 0.72
SCHEMBL11980576 0.72
SCHEMBL8649346 0.72

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 22450 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12042495-B2 MAP4K1 inhibitors BLUEPRINT MEDICINES CORPORATION (US) 2024-07-23 US claimed
US-20240239804-A1 FUROINDAZOLE DERIVATIVES AS ANTAGONISTS OR INHIBITORS OF GPR84 BAYER AKTIENGESELLSCHAFT (DE) 2024-07-18 US claimed
WO-2024149189-A1 AROMATIC AMIDE DERIVATIVE, PREPARATION METHOD THEREFOR, AND USE THEREOF 浙江海正药业股份有限公司 2024-07-18 WO claimed
US-20240238445-A1 INHIBITORS AND USES THEREOF NEURACLE SCIENCE CO., LTD. (KR) 2024-07-18 US claimed
CN-118344315-A Preparation and application of trifluoro thioether (sulfoxide) aromatic amine derivative 顺毅股份有限公司 2024-07-16 CN claimed
WO-2024146383-A1 CYP11A1 INHIBITOR COMPOUND, AND PREPARATION METHOD THEREFOR AND USE THEREOF 上海闻耐医药科技有限公司 2024-07-11 WO claimed
US-20240228506-A1 RIPK1 INHIBITORS AND METHODS OF USE MERCK SHARP & DOHME LLC (US) 2024-07-11 US claimed
CN-118307519-A CYP11A1 inhibitor compound, preparation method and application thereof 上海闻耐医药科技有限公司 2024-07-09 CN claimed
WO-2024140433-A2 ANTIBODY-DRUG CONJUGATE CONTAINING N-METHYLENE AMIDE LINKER 杭州爱科瑞思生物医药有限公司 2024-07-04 WO claimed
EP-4392419-A1 NOVEL PYRAZINYL-TRIAZOLE COMPOUNDS AS PESTICIDES Bayer Aktiengesellschaft (DE) 2024-07-03 EP claimed
EP-0285565-A2 2-Mercapto-5-pyridyl-1,3,4-oxadiazoles and 1,3,4-thiadiazoles, process for their preparation and their use as nematicidal agents CIBA-GEIGY AG (CH) 1988-10-05 EP claimed
US-4699916-A Substituted furazan pesticides BAYER AKTIENGESELLSCHAFT (DE) 1987-10-13 US claimed
EP-0093977-B1 2,5-DIHALOGENBENZOYL UREAS AND THIOUREAS, PROCESSES FOR THEIR PREPARATION AND THEIR USE AS PESTICIDES BAYER AG (DE) 1987-08-05 EP claimed
EP-0230053-A2 7-(Substituted)piperazinyl-1-ethyl-6-fluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylic acids AMERICAN CYANAMID COMPANY (US) 1987-07-29 EP claimed
EP-0132680-B1 SUBSTITUTED FURAZANS BAYER AG (DE) 1987-01-28 EP claimed
US-4533676-A 2,5-Dihalogenobenzoyl-(thio)urea insecticides BAYER AKTIENGESELLSCHAFT (DE) 1985-08-06 US claimed
EP-0132680-A1 Substituted furazans BAYER AG (DE) 1985-02-13 EP claimed
EP-0115828-A1 Substituted oxime ether BAYER AG (DE) 1984-08-15 EP claimed
EP-0093977-A1 2,5-Dihalogenbenzoyl ureas and thioureas, processes for their preparation and their use as pesticides BAYER AG (DE) 1983-11-16 EP claimed
EP-0093976-A1 2,4-Dihalogenbenzoyl ureas and thioureas, processes for their preparation and their use as pesticides BAYER AG (DE) 1983-11-16 EP claimed