Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | C1S | P09871 | 15/20 | 0.78 |
| ▸ | PLG | P00747 | 1/20 | 0.71 |
| ▸ | PLAT | P00750 | 1/20 | 0.71 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.71 |
| ▸ | PLAU | P00749 | 9/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7470625 | 0.99 | C1S (0.77) | C1SPLGPLATPRSS1PLAU | |
| SCHEMBL6434656 | 0.89 | C1S (0.86) | C1SPLGPLATPRSS1PLAU | |
| Hydrochloric Acid SCHEMBL6925110 | 0.88 | C1S (0.85) | C1SPLGPLATPRSS1PLAU | |
| SCHEMBL6927513 | 0.88 | C1S (1.00) | C1SPLGPLATPRSS1PLAU | |
| Hydrochloric Acid SCHEMBL6921856 | 0.87 | C1S (0.98) | C1SPLGPLATPRSS1PLAU | |
| SCHEMBL6921141 | 0.85 | C1S (1.00) | C1SPLGPLATPRSS1PLAU | |
| Hydrochloric Acid SCHEMBL6926241 | 0.85 | C1S (0.98) | C1SPLGPLATPRSS1PLAU | |
| SCHEMBL6927408 | 0.83 | C1S (1.00) | C1SPLGPLATPRSS1PLAU | |
| SCHEMBL6927390 | 0.82 | C1S (0.82) | C1SPLGPLATPRSS1PLAU | |
| Hydrochloric Acid SCHEMBL6920446 | 0.82 | C1S (0.98) | C1SPLGPLATPRSS1PLAU |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6403633-B2 | USEFUL ANTIANGIOGENIC, ANTIARTHRITIC, ANTIINFLAMMATORY, ANTIRESTENOTIC, ANTIINVASIVE, ANTIMETASTIC, ANTIOSTEOPOROTIC, ANTIRETINOPATHIC, CONTRACEPTIVE AND TUMORISTATIC TREATMENT AGENTS | 3-DIMENSIONAL PHARMACEUTICALS, INC. | 2002-06-11 | — | — | US | claimed |