Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNF | P01375 | 14/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7139116 | 0.87 | KDM4E (0.45) | ALDH1A1 | |
| SCHEMBL6848920 | 0.81 | TNF (0.50) | TNFALDH1A1KAT2BLMNA | |
| SCHEMBL6848928 | 0.80 | TNF (0.49) | TNFALDH1A1KAT2BLMNA | |
| SCHEMBL28415185 | 0.76 | TNF (0.47) | TNFALDH1A1KAT2BLMNA | |
| SCHEMBL6850252 | 0.76 | F2 (0.56) | ALDH1A1 | |
| SCHEMBL6848933 | 0.76 | TNF (0.40) | TNFALDH1A1KAT2BLMNA | |
| SCHEMBL6850182 | 0.76 | KDM4E (0.42) | TNFALDH1A1 | |
| SCHEMBL7139240 | 0.75 | F2 (0.44) | — | |
| SCHEMBL11210438 | 0.69 | TNF (0.52) | TNFALDH1A1KAT2BLMNA | |
| SCHEMBL5885705 | 0.67 | KDM4E (0.49) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6777431-B2 | ANTICOAGULANTS | CORVAS INTERNATIONAL, INC. | 2004-08-17 | — | — | US | disclosed |
| US-6777431-B2 | ANTICOAGULANTS | CORVAS INTERNATIONAL, INC. | 2004-08-17 | — | — | US | disclosed |