Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.38 |
| ▸ | DHODH | Q02127 | 3/20 | 0.38 |
| ▸ | SYK | P43405 | 3/20 | 0.37 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.35 |
| ▸ | BRS3 | P32247 | 2/20 | 0.35 |
| ▸ | ALB | P02768 | 1/20 | 0.35 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.35 |
| ▸ | ANPEP | P15144 | 1/20 | 0.34 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | IDO1 | P14902 | 1/20 | 0.34 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.34 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.34 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.34 |
| ▸ | RARB | P10826 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | RARA | P10276 | 1/20 | 0.34 |
| ▸ | RARG | P13631 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7737092 | 0.87 | CD274 (0.39) | CD274DHODHSYKFFAR4ALB | |
| SCHEMBL7728586 | 0.85 | CD274 (0.35) | CD274DHODHSYKFFAR4ALB | |
| SCHEMBL7736040 | 0.83 | CD274 (0.41) | CD274DHODHSYKALBACMSD | |
| SCHEMBL7737258 | 0.81 | CD274 (0.37) | CD274DHODHSYKBRS3ALB | |
| SCHEMBL7736705 | 0.80 | CD274 (0.38) | CD274DHODHSYKALBACMSD | |
| SCHEMBL7728663 | 0.79 | LTB4R2 (0.39) | CD274DHODHSYKBRS3RARB | |
| SCHEMBL7728743 | 0.78 | RARB (0.40) | CD274DHODHBRS3RARBRARA | |
| SCHEMBL7736033 | 0.78 | CD274 (0.37) | CD274DHODHSYKFFAR4BRS3 | |
| SCHEMBL7737257 | 0.78 | DHODH (0.38) | CD274DHODHFFAR4ALBACMSD | |
| SCHEMBL7728584 | 0.78 | DHODH (0.38) | CD274DHODHFFAR4ALBACMSD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6468606-B1 | LOW VISCOSITY, HIGH DIELECTRIC ANISOTROPY, LOW OPTICAL ANISOTROPY, EXCELLENT LOW TEMPERATURE COMPATIBILITY WITH OTHER LIQUID CRYSTALLINE COMPOUNDS; 3,4,5-TRIFLUOROPHENYL-(2-FLUORO-4-(TRANS-4-PROPYLCYCLOHEXYL))BENZOATE | CHISSO CORPORATION (JP) | 2002-10-22 | — | — | US | disclosed |
| EP-0808825-B1 | PHENYL BENZOATE DERIVATIVES AND LIQUID CRYSTAL COMPOSITIONS | CHISSO CORP (JP) | 2001-09-12 | — | — | EP | disclosed |
| US-5922243-A | LOW VISCOSITY, HIGH DIELECTRIC AND LOW OPTICAL ANISOTROPY, EXCELLENT COMPATIBILITY | CHISSO CORPORATION (JP) | 1999-07-13 | — | — | US | disclosed |
| EP-0808825-A1 | PHENYL BENZOATE DERIVATIVES AND LIQUID CRYSTAL COMPOSITIONS | CHISSO CORPORATION (JP) | 1997-11-26 | — | — | EP | disclosed |