Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPRB | P23467 | 11/20 | 0.48 |
| ▸ | PTPN2 | P17706 | 2/20 | 0.37 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.37 |
| ▸ | PTPRA | P18433 | 1/20 | 0.37 |
| ▸ | ACP1 | P24666 | 1/20 | 0.37 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.37 |
| ▸ | GHSR | Q92847 | 5/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA7 | P43166 | 1/20 | 0.36 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7742069 | 0.89 | PTPRB (0.50) | PTPRBPTPN2PTPN1PTPRAACP1 | |
| SCHEMBL2992285 | 0.83 | PTPRB (0.40) | PTPRBCA12CA1CA7CA14 | |
| SCHEMBL2982545 | 0.83 | PTPRB (0.40) | PTPRBCA12CA1CA7CA14 | |
| SCHEMBL7742081 | 0.81 | PTPRB (0.42) | PTPRBPTPN1LMNASMN1; SMN2 | |
| SCHEMBL7742079 | 0.81 | PTPRB (0.42) | PTPRBPTPN1LMNASMN1; SMN2 | |
| SCHEMBL3935734 | 0.76 | PPARG (0.49) | LMNASMN1; SMN2 | |
| SCHEMBL3935728 | 0.76 | PPARG (0.49) | LMNASMN1; SMN2 | |
| SCHEMBL7736843 | 0.74 | PTPRB (0.47) | PTPRBHTT | |
| SCHEMBL2711160 | 0.74 | CA12 (0.50) | CA12CA1CA7CA14 | |
| SCHEMBL5146278 | 0.73 | ITGB1 (0.47) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6420424-B1 | ADMINISTERING PHENYLALANINE AMIDE DERIVATIVES (SUCH AS S-ETHYL-2-AMINO-3-(4-CHLOROPHENYL)PROPIONATE HYDROCHLORIDE) TO TREAT ALLERGIC DISORDERS, INCLUDING ASTHMA, RHINITIS, DERMATITUS, AND PRURITIS | SMITHKLINE BEECHAM CORPORATION | 2002-07-16 | — | — | US | disclosed |