SCHEMBL7736868

SCHEMBL7736868

CO/C=C(/C(=O)OC)c1ccccc1CO/N=C(C)/C(=N\OC)c1ccc(OCc2cccc(C(F)(F)F)c2)cc1F

nearest known ligand 0.53

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
HIF1A Q16665 7/20 0.53
MAPT P10636 1/20 0.45
HTT P42858 1/20 0.45
L3MBTL1 Q9Y468 1/20 0.45
MAOB P27338 6/20 0.41
S1PR1 P21453 1/20 0.39
PRKX P51817 1/20 0.39
IKBKE Q14164 1/20 0.39
S1PR5 Q9H228 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7736870 1.00 HIF1A (0.53) HIF1AMAPTHTTL3MBTL1MAOB
SCHEMBL6839881 0.91 HIF1A (0.53) HIF1AMAPTHTTL3MBTL1MAOB
SCHEMBL7497475 0.90 HIF1A (0.48) HIF1AMAPTHTTL3MBTL1MAOB
SCHEMBL7497471 0.90 HIF1A (0.48) HIF1AMAPTHTTL3MBTL1MAOB
SCHEMBL7742949 0.88 HIF1A (0.48) HIF1AMAPTHTTL3MBTL1MAOB
SCHEMBL7742946 0.88 HIF1A (0.48) HIF1AMAPTHTTL3MBTL1MAOB
SCHEMBL7741767 0.86 HIF1A (0.43) HIF1A
SCHEMBL7741766 0.86 HIF1A (0.43) HIF1A
SCHEMBL7465781 0.85 MAOB (0.47) HIF1AMAPTHTTL3MBTL1MAOB
SCHEMBL7465783 0.85 MAOB (0.47) HIF1AMAPTHTTL3MBTL1MAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6420423-B1 PESTICIDE FOR USE ON CEREALS, BEETS, FRUITS, BERRIES, AND BEANS; KILLS MITES, INSECTS, TERMITES, LICE, FLEAS, AND FUNGUS; TOLERATED WELL BE ANIMALS, PLANTS, AND FISH BAYER AKTIENGESELLSCHAFT (DE) 2002-07-16 US disclosed
US-5985921-A OXIDATION AND HYDROGENATION OF COMPOUNDS TO FORM INSECTICIDES AS AGROCHEMICALS NOVARTIS CORPORATION (US) 1999-11-16 US disclosed