SCHEMBL7737232

SCHEMBL7737232

C=CCC1CCC(c2ccc(I)cc2)CC1

nearest known ligand 0.41

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
ESR2 Q92731 12/20 0.41
ESR1 P03372 6/20 0.41
CYP2C9 P11712 3/20 0.41
CYP3A4 P08684 2/20 0.41
CYP2D6 P10635 1/20 0.37
POLB P06746 1/20 0.34
ALDH1A1 P00352 1/20 0.32
LMNA P02545 1/20 0.32
MAPT P10636 1/20 0.32
MEN1 O00255 1/20 0.32
MAPK1 P28482 1/20 0.32
KMT2A Q03164 1/20 0.32
IDO1 P14902 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10778231 0.95 ESR2 (0.38) ESR2ESR1CYP2C9CYP3A4CYP2D6
SCHEMBL11134889 0.91 ESR2 (0.35) ESR2ESR1CYP2C9CYP3A4CYP2D6
SCHEMBL11134892 0.91 ESR2 (0.35) ESR2ESR1CYP2C9CYP3A4CYP2D6
SCHEMBL11210601 0.91 ESR2 (0.47) ESR2ESR1CYP2C9CYP3A4CYP2D6
SCHEMBL11210597 0.91 ESR2 (0.47) ESR2ESR1CYP2C9CYP3A4CYP2D6
SCHEMBL10935701 0.85 ESR2 (0.43) ESR2ESR1CYP2C9CYP3A4CYP2D6
SCHEMBL10904861 0.85 ESR2 (0.43) ESR2ESR1CYP2C9CYP3A4CYP2D6
SCHEMBL11217896 0.85 ESR2 (0.43) ESR2ESR1CYP2C9CYP3A4CYP2D6
SCHEMBL11217898 0.85 ESR2 (0.43) ESR2ESR1CYP2C9CYP3A4CYP2D6
SCHEMBL10935713 0.85 ESR2 (0.43) ESR2ESR1CYP2C9CYP3A4CYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6468606-B1 LOW VISCOSITY, HIGH DIELECTRIC ANISOTROPY, LOW OPTICAL ANISOTROPY, EXCELLENT LOW TEMPERATURE COMPATIBILITY WITH OTHER LIQUID CRYSTALLINE COMPOUNDS; 3,4,5-TRIFLUOROPHENYL-(2-FLUORO-4-(TRANS-4-PROPYLCYCLOHEXYL))BENZOATE CHISSO CORPORATION (JP) 2002-10-22 US disclosed
EP-0808825-B1 PHENYL BENZOATE DERIVATIVES AND LIQUID CRYSTAL COMPOSITIONS CHISSO CORP (JP) 2001-09-12 EP disclosed
US-5922243-A LOW VISCOSITY, HIGH DIELECTRIC AND LOW OPTICAL ANISOTROPY, EXCELLENT COMPATIBILITY CHISSO CORPORATION (JP) 1999-07-13 US disclosed
EP-0808825-A1 PHENYL BENZOATE DERIVATIVES AND LIQUID CRYSTAL COMPOSITIONS CHISSO CORPORATION (JP) 1997-11-26 EP disclosed