Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.46 |
| ▸ | SIRT6 | Q8N6T7 | 2/20 | 0.44 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15059997 | 0.82 | FFAR1 (0.44) | MAPK1ALDH1A1MEN1KMT2A | |
| SCHEMBL2572245 | 0.81 | CNR1 (0.53) | AKR1C3LMNAMAPK1ALDH1A1SMN1; SMN2 | |
| SCHEMBL2572244 | 0.81 | CNR1 (0.53) | AKR1C3LMNAMAPK1ALDH1A1SMN1; SMN2 | |
| SCHEMBL31480949 | 0.79 | KMT2A (0.47) | MAPTSIRT6LMNAMAPK1ALDH1A1 | |
| SCHEMBL15060430 | 0.77 | MEN1 (0.41) | LMNAMAPK1ALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL9103501 | 0.77 | CNR1 (0.56) | MAPTAKR1C3LMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL9103491 | 0.77 | CNR1 (0.56) | MAPTAKR1C3LMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL14637947 | 0.75 | MAPT (0.55) | MAPTSIRT6AKR1C3LMNAMAPK1 | |
| Ammonia Solution, Strong SCHEMBL27868466 | 0.75 | MAPT (0.54) | MAPTSIRT6AKR1C3LMNAALDH1A1 | |
| SCHEMBL6608147 | 0.72 | MAPT (0.63) | MAPTSIRT6AKR1C3LMNAMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6423772-B1 | POLYSILSESQUIOXANES | INSTITUTE OF CHEMISTRY, CHINESE ACADEMY OF SCIENCES | 2002-07-23 | — | — | US | claimed |
| WO-1999003910-A1 | TUBE-LIKE ORGANOSILICON POLYMERIC COMPLEXES AND THE METHOD FOR PRODUCING THE SAME | INSTITUTE OF CHEMISTRY, CHINESE ACADEMY OF SCIENCES (CN) | 1999-01-28 | — | — | WO | claimed |
| WO-1999003910-A1 | TUBE-LIKE ORGANOSILICON POLYMERIC COMPLEXES AND THE METHOD FOR PRODUCING THE SAME | INSTITUTE OF CHEMISTRY, CHINESE ACADEMY OF SCIENCES (CN) | 1999-01-28 | — | — | WO | disclosed |