Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.38 |
| ▸ | BLM | P54132 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | GABRR1 | P24046 | 2/20 | 0.38 |
| ▸ | GABRR2 | P28476 | 2/20 | 0.38 |
| ▸ | GABRR3 | A8MPY1 | 1/20 | 0.38 |
| ▸ | APEX1 | P27695 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | CNR1 | P21554 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | PPARA | Q07869 | 1/20 | 0.34 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.33 |
| ▸ | DDAH1 | O94760 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.32 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30262989 | 0.94 | TSHR (0.41) | TSHRBLMLMNAGABRR1GABRR2 | |
| SCHEMBL28069237 | 0.94 | TSHR (0.41) | TSHRBLMLMNAGABRR1GABRR2 | |
| SCHEMBL33774 | 0.94 | TSHR (0.41) | TSHRBLMLMNAGABRR1GABRR2 | |
| Acetamide SCHEMBL27877987 | 0.92 | BLM (0.44) | TSHRBLMLMNAGABRR1GABRR2 | |
| SCHEMBL28328042 | 0.91 | TSHR (0.39) | TSHRBLMLMNAGABRR1GABRR2 | |
| Ammonia Solution, Strong SCHEMBL27914658 | 0.91 | TSHR (0.39) | TSHRBLMLMNAGABRR1GABRR2 | |
| SCHEMBL28057882 | 0.91 | TSHR (0.39) | TSHRBLMLMNAGABRR1GABRR2 | |
| Ammonia Solution, Strong SCHEMBL27750230 | 0.91 | TSHR (0.39) | TSHRBLMLMNAGABRR1GABRR2 | |
| Acetic Acid SCHEMBL28330326 | 0.89 | TSHR (0.40) | TSHRBLMLMNAGABRR1GABRR2 | |
| Alcohol SCHEMBL28273467 | 0.89 | CNR1 (0.38) | TSHRBLMLMNAGABRR1GABRR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6413941-B1 | ANTICANCER AGENTS | WEST PHARMACEUTICAL SERVICES DRUG DELIVERY & CLINICAL RESEARCH CENTRE LIMITED (GB) | 2002-07-02 | — | — | US | disclosed |