Oleanolic_Acid

Oleanolic_Acid

SCHEMBL7739312

CC1(C)CCC2(C(=O)O)CC[C@]3(C)C(=CCC4[C@@]5(C)CCC(O)C(C)(C)[C@@H]5CC[C@]43C)C2C1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTPN1 P18031 12/20 1.00
PTPN2 P17706 4/20 1.00
F3 P13726 4/20 1.00
POLB P06746 3/20 1.00
USP7 Q93009 3/20 1.00
AKR1B10 O60218 3/20 1.00
GPBAR1 Q8TDU6 3/20 1.00
PSMB11 A5LHX3 2/20 1.00
PSMA7 O14818 2/20 1.00
PLA2G1B P04054 2/20 1.00
PTPRC P08575 2/20 1.00
PTPRF P10586 2/20 1.00
PSMB1 P20618 2/20 1.00
CES1 P23141 2/20 1.00
ACP1 P24666 2/20 1.00
PSMA1 P25786 2/20 1.00
PSMA2 P25787 2/20 1.00
PSMA3 P25788 2/20 1.00
PSMA4 P25789 2/20 1.00
PSMB8 P28062 2/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Oleanolic_Acid SCHEMBL15714063 1.00 PTPN1 (1.00) PTPN1PTPN2F3POLBUSP7
Oleanolic_Acid SCHEMBL12337275 1.00 PTPN1 (1.00) PTPN1PTPN2F3POLBUSP7
Oleanolic_Acid SCHEMBL18420569 1.00 PTPN1 (1.00) PTPN1PTPN2F3POLBUSP7
Oleanolic_Acid SCHEMBL13425080 1.00 PTPN1 (1.00) PTPN1PTPN2F3POLBUSP7
Oleanolic_Acid SCHEMBL13395360 1.00 PTPN1 (1.00) PTPN1PTPN2F3POLBUSP7
Oleanolic_Acid SCHEMBL16153016 1.00 PTPN1 (1.00) PTPN1PTPN2F3POLBUSP7
Oleanolic_Acid SCHEMBL24916648 1.00 PTPN1 (1.00) PTPN1PTPN2F3POLBUSP7
Oleanolic_Acid SCHEMBL21892159 1.00 PTPN1 (1.00) PTPN1PTPN2F3POLBUSP7
Oleanolic_Acid SCHEMBL22009261 1.00 PTPN1 (1.00) PTPN1PTPN2F3POLBUSP7
Oleanolic_Acid SCHEMBL20904290 1.00 PTPN1 (1.00) PTPN1PTPN2F3POLBUSP7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7465466-B2 Compositions and methods for prostate and kidney health and disorders, an herbal preparation INTEGRATED CHINESE MEDICINE HOLDINGS, LTD. (HK) 2008-12-16 US disclosed
US-7449202-B1 Compositions and methods for prostate and kidney health and disorders, an herbal preparation INTEGRATED CHINESE MEDICINE HOLDINGS, LTD. (HK) 2008-11-11 US disclosed
US-7223424-B2 Compositions and methods for prostate and kidney health and disorders, an herbal preparation INTEGRATED CHINESE MEDICINE HOLDINGS, LTD. (HK) 2007-05-29 US disclosed