Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.58 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.58 |
| ▸ | HRH3 | Q9Y5N1 | 12/20 | 0.51 |
| ▸ | HRH4 | Q9H3N8 | 5/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | GLA | P06280 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15228060 | 0.96 | CYP3A4 (0.57) | CYP3A4SLC7A5HRH3HRH4MEN1 | |
| SCHEMBL7779386 | 0.95 | CYP3A4 (0.56) | CYP3A4SLC7A5HRH3HRH4 | |
| SCHEMBL7781926 | 0.95 | CYP3A4 (0.56) | CYP3A4SLC7A5HRH3HRH4 | |
| SCHEMBL7780217 | 0.95 | CYP3A4 (0.56) | CYP3A4SLC7A5HRH3HRH4 | |
| SCHEMBL28031774 | 0.94 | CYP3A4 (0.55) | CYP3A4SLC7A5HRH3HRH4 | |
| SCHEMBL28221698 | 0.94 | CYP3A4 (0.55) | CYP3A4SLC7A5HRH3HRH4 | |
| SCHEMBL28032325 | 0.94 | CYP3A4 (0.55) | CYP3A4SLC7A5HRH3HRH4 | |
| SCHEMBL6436202 | 0.92 | CYP3A4 (0.61) | CYP3A4SLC7A5HRH3HRH4MEN1 | |
| SCHEMBL7300956 | 0.90 | CYP3A4 (0.53) | CYP3A4SLC7A5HRH3HRH4 | |
| SCHEMBL18878730 | 0.87 | CYP3A4 (0.56) | CYP3A4SLC7A5HRH3HRH4MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6410680-B1 | STRESS RESISTANCE THERAPY | DENDRIMOLECULAR, INC. | 2002-06-25 | — | — | US | claimed |
| CN-112074737-A | Compositions and methods for evaluating listeria strains for attenuation and infectivity | 阿德瓦希斯公司 | 2020-12-11 | — | — | CN | disclosed |
| CN-111356760-A | Lyophilized compositions and methods of bacteria or listeria strains | 阿德瓦希斯公司 | 2020-06-30 | — | — | CN | disclosed |
| EP-0192554-B1 | PEPTIDE DERIVATIVES INHIBITING RENIN AND ACID PROTEASES | SANOFI (FR) | 1992-01-02 | — | — | EP | disclosed |
| EP-0192554-A1 | Peptide derivatives inhibiting renin and acid proteases | SANOFI (FR) | 1986-08-27 | — | — | EP | disclosed |