SCHEMBL774064

SCHEMBL774064

C[C@@H]1CCCCC1=O

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20714 1.00
SCHEMBL43572 1.00
SCHEMBL2348541 0.97 KMT2A (1.00)
SCHEMBL2344671 0.97 KMT2A (1.00)
SCHEMBL5502600 0.97 CA1 (0.95)
SCHEMBL16657576 0.97
SCHEMBL107928 0.97
SCHEMBL2340771 0.97 KMT2A (1.00)
SCHEMBL2344609 0.97 KMT2A (1.00)
SCHEMBL2350406 0.97 KMT2A (1.00)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115851778-B Thermophilic alkene reductase from aspergillus flavus, expression vector and application thereof 河南工业大学 2024-10-01 CN disclosed
CN-114875106-B Method for generating (S) -2-methylcyclohexanone by utilizing alkene reductase in micro-flow field 南京工业大学 2023-11-24 CN disclosed
CN-114875106-B Method for generating (S) -2-methylcyclohexanone by utilizing alkene reductase in micro-flow field 南京工业大学 2023-11-24 CN disclosed
US-20230206644-A1 PYRAZOLOPYRIMIDINE COMPOUNDS AS JAK INHIBITORS GENENTECH, INC. (US) 2023-06-29 US disclosed
CN-115851778-A Thermophilic alkene reductase from aspergillus flavus, expression vector and application thereof 河南工业大学 2023-03-28 CN disclosed
CN-114875106-A Method for generating (S) -2-methylcyclohexanone by using alkene reductase in micro-flow field 南京工业大学 2022-08-09 CN disclosed
CN-114875106-A Method for generating (S) -2-methylcyclohexanone by using alkene reductase in micro-flow field 南京工业大学 2022-08-09 CN disclosed
US-20220169580-A1 METHODS OF CARBON-CARBON BOND FRAGMENTATION THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2022-06-02 US disclosed
US-11236082-B2 EZH2 inhibitors and uses thereof DANA-FARBER CANCER INSTITUTE, INC. (US) 2022-02-01 US disclosed
US-20200339604-A1 PYRAZOLOPYRIMIDINE COMPOUNDS AS JAK INHIBITORS GENENTECH, INC. (US) 2020-10-29 US disclosed
US-20130045513-A1 PROCESS FOR THE ENZYMATIC REDUCTION OF ENOATES BASF SE (DE) 2013-02-21 US disclosed
US-20130045513-A1 PROCESS FOR THE ENZYMATIC REDUCTION OF ENOATES BASF SE (DE) 2013-02-21 US disclosed
US-20120232076-A1 QUINOLIZIDINONE CARBOXAMIDE M1 RECEPTOR POSITIVE ALLOSTERIC MODULATORS MERCK SHARP & DOHME LLC 2012-09-13 US disclosed
US-20120070867-A1 PROCESS FOR THE ENZYMATIC REDUCTION OF ENOATES BASF SE (DE) 2012-03-22 US disclosed
US-20120070867-A1 PROCESS FOR THE ENZYMATIC REDUCTION OF ENOATES BASF SE (DE) 2012-03-22 US disclosed
US-20110039888-A1 ASYMMETRIC ALPHA FUNCTIONALIZATION AND ALPHA, ALPHA BISFUNCTIONALIZATION OF ALDEHYDES AND KETONES COLTART DON M 2011-02-17 US disclosed
WO-2010139651-A2 A PROCESS FOR THE ENZYMATIC REDUCTION OF ENOATES BASF SE (DE) 2010-12-09 WO disclosed
WO-2010075574-A2 ENONE REDUCTASES CODEXIS, INC. (US) 2010-07-01 WO disclosed
WO-2007051255-A1 PROCESS FOR THE PREPARATION OF COMPOUNDS CONTAINING AN AZACYCLIC RING SYSTEM THE UNIVERSITY OF SYDNEY (AU) 2007-05-10 WO disclosed
US-5250426-A Catalytic hydrolysis using monoclonal antibodies THE SCRIPPS RESEARCH INSTITUTE (US) 1993-10-05 US disclosed