Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 8/20 | 0.44 |
| ▸ | ESR1 | P03372 | 6/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | GALR1 | P47211 | 1/20 | 0.35 |
| ▸ | KDM1A | O60341 | 1/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7741316 | 1.00 | ESR2 (0.44) | ESR2ESR1CYP2C9CYP3A4CYP2D6 | |
| SCHEMBL10864824 | 0.88 | NPC1 (0.47) | ESR2ESR1CYP2C9CYP3A4KDM1A | |
| SCHEMBL19850825 | 0.86 | ESR2 (0.41) | ESR2ESR1CYP2C9CYP3A4MAPT | |
| SCHEMBL7912624 | 0.86 | ESR2 (0.41) | ESR2ESR1CYP2C9CYP3A4MAPT | |
| SCHEMBL8034648 | 0.86 | ESR2 (0.41) | ESR2ESR1CYP2C9CYP3A4MAPT | |
| SCHEMBL8038575 | 0.86 | ESR2 (0.41) | ESR2ESR1CYP2C9CYP3A4MAPT | |
| SCHEMBL7912629 | 0.86 | ESR2 (0.41) | ESR2ESR1CYP2C9CYP3A4MAPT | |
| SCHEMBL8034940 | 0.85 | ESR2 (0.40) | ESR2ESR1CYP2C9CYP3A4MAPT | |
| SCHEMBL8034935 | 0.85 | ESR2 (0.40) | ESR2ESR1CYP2C9CYP3A4MAPT | |
| SCHEMBL8034938 | 0.85 | ESR2 (0.40) | ESR2ESR1CYP2C9CYP3A4MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0891314-B1 | BISALKENYL DERIVATIVES, LIQUID CRYSTALLINE COMPOUNDS AND LIQUID CRYSTAL COMPOSITIONS | CHISSO CORP (JP) | 2001-09-05 | — | — | EP | disclosed |
| US-6180027-B1 | DISPLAY DEVICE | CHISSO CORPORATION (JP) | 2001-01-30 | — | — | US | disclosed |
| EP-0891314-A1 | BISALKENYL DERIVATIVES, LIQUID CRYSTALLINE COMPOUNDS AND LIQUID CRYSTAL COMPOSITIONS | CHISSO CORPORATION (JP) | 1999-01-20 | — | — | EP | disclosed |
| WO-1997034855-A1 | BISALKENYL DERIVATIVES, LIQUID CRYSTALLINE COMPOUNDS AND LIQUID CRYSTAL COMPOSITIONS | CHISSO CORPORATION (JP) | 1997-09-25 | — | — | WO | disclosed |