Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK5 | Q00535 | 1/20 | 0.42 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.42 |
| ▸ | NR1I3 | Q14994 | 1/20 | 0.42 |
| ▸ | GRIN1 | Q05586 | 3/20 | 0.42 |
| ▸ | GRIN2B | Q13224 | 3/20 | 0.42 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.40 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4729969 | 0.89 | SRD5A1 (0.52) | SRD5A1SRD5A2 | |
| SCHEMBL5596630 | 0.89 | SRD5A1 (0.52) | SRD5A1SRD5A2 | |
| SCHEMBL1552900 | 0.89 | SRD5A1 (0.52) | SRD5A1SRD5A2 | |
| SCHEMBL9620174 | 0.84 | SRD5A2 (0.42) | CDK5CDK5R1NR1I3GRIN1GRIN2B | |
| SCHEMBL8076029 | 0.82 | NR1I3 (0.47) | CDK5CDK5R1NR1I3GRIN1GRIN2B | |
| SCHEMBL8158079 | 0.80 | SRD5A1 (0.42) | CDK5CDK5R1NR1I3GRIN1GRIN2B | |
| SCHEMBL7741691 | 0.75 | SRD5A2 (0.41) | GRIN1GRIN2BSRD5A1SRD5A2 | |
| SCHEMBL7711773 | 0.74 | GRIN1 (0.40) | CDK5CDK5R1NR1I3GRIN1GRIN2B | |
| SCHEMBL7802581 | 0.73 | SRD5A1 (0.58) | SRD5A1SRD5A2 | |
| SCHEMBL7527164 | 0.73 | SRD5A1 (0.58) | SRD5A1SRD5A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6420352-B1 | TOPICAL COMPOSITION COMPRISING 5 ALPHA-REDUCTASE INHIBITOR, MINOXIDIL, TRIMETHYL ACETATE | KNOWLES W ROY (US) | 2002-07-16 | — | — | US | disclosed |