Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 1/20 | 0.50 |
| ▸ | CES1 | P23141 | 5/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | CES2 | O00748 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL34466536 | 0.85 | SRC (0.50) | SRCCES1LMNAPOLBNPSR1 | |
| SCHEMBL11371306 | 0.82 | CES1 (0.47) | SRCCES1LMNAPOLBNPSR1 | |
| SCHEMBL11251806 | 0.81 | CES1 (0.46) | SRCCES1LMNAPOLBNPSR1 | |
| SCHEMBL9004611 | 0.81 | CES1 (0.46) | SRCCES1LMNACES2ALDH1A1 | |
| SCHEMBL251616 | 0.80 | CES1 (0.50) | SRCCES1LMNAPOLBNPSR1 | |
| SCHEMBL10446200 | 0.79 | CES1 (0.53) | SRCCES1LMNAPOLBNPSR1 | |
| SCHEMBL34466866 | 0.79 | CES1 (0.44) | SRCCES1LMNAPOLBNPSR1 | |
| SCHEMBL27768512 | 0.79 | CES1 (0.44) | SRCCES1LMNAPOLBNPSR1 | |
| SCHEMBL9005043 | 0.79 | CES1 (0.44) | SRCCES1LMNAPOLBNPSR1 | |
| SCHEMBL36702 | 0.78 | CES1 (0.66) | SRCCES1LMNAPOLBNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-H2043-H1 | CONTAINING RETINOIDS | THE PROCTER & GAMBLE COMPANY | 2002-08-06 | — | — | US | disclosed |