Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 4/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | CRHBP | P24387 | 1/20 | 0.45 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7745852 | 0.87 | CYP3A4 (0.59) | CYP3A4TSHRNPSR1SMN1; SMN2CRHBP | |
| SCHEMBL7746055 | 0.86 | CYP3A4 (0.72) | CYP3A4TSHRNPSR1SMN1; SMN2CRHBP | |
| SCHEMBL8366214 | 0.85 | CYP3A4 (0.54) | CYP3A4TSHRNPSR1SMN1; SMN2CRHBP | |
| SCHEMBL7741415 | 0.81 | TSHR (0.39) | CYP3A4TSHRSMN1; SMN2ALDH1A1POLB | |
| SCHEMBL6479793 | 0.80 | CYP3A4 (0.50) | CYP3A4TSHRNPSR1SMN1; SMN2CRHBP | |
| SCHEMBL6783757 | 0.78 | CYP3A4 (0.54) | CYP3A4TSHRNPSR1SMN1; SMN2CRHBP | |
| SCHEMBL6247449 | 0.77 | CYP3A4 (0.49) | CYP3A4TSHRNPSR1SMN1; SMN2CRHBP | |
| SCHEMBL6274097 | 0.76 | CYP3A4 (0.58) | CYP3A4TSHRNPSR1SMN1; SMN2CRHBP | |
| SCHEMBL7891212 | 0.75 | NPSR1 (0.46) | CYP3A4TSHRNPSR1SMN1; SMN2CRHBP | |
| SCHEMBL7747798 | 0.73 | MEN1 (0.41) | TSHRSMN1; SMN2POLBL3MBTL1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6774134-B2 | FOR THERAPY OF RESPIRATORY SYNCYTIAL VIRUS INFECTION | BRISTOL-MYERS SQUIBB COMPANY | 2004-08-10 | — | — | US | disclosed |