Methacrylic Acid

Methacrylic Acid

SCHEMBL7741798

C=C(C)C(=O)O.C=C(C)C(=O)OCC(C)CC(=O)O

nearest known ligand 0.58

Full drug profile on Sugi Atlas →

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.58
THRB P10828 1/20 0.38
ALDH1A1 P00352 2/20 0.36
POLB P06746 1/20 0.32
APEX1 P27695 1/20 0.32
HTT P42858 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
ITGB3 P05106 1/20 0.31
ITGA2B P08514 1/20 0.31
BHMT Q93088 1/20 0.30
ALOX15 P16050 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15372542 0.96 TSHR (0.62) TSHRTHRBALDH1A1POLBAPEX1
SCHEMBL20006488 0.83 TSHR (0.64) TSHRTHRBALDH1A1POLBAPEX1
SCHEMBL3319370 0.82 TSHR (0.75) TSHRTHRBALDH1A1POLBAPEX1
Methacrylic Acid SCHEMBL1472434 0.81 TSHR (0.88) TSHRTHRBALDH1A1POLBAPEX1
SCHEMBL20001266 0.81 TSHR (0.72) TSHRTHRBALDH1A1POLBAPEX1
Methacrylic Acid SCHEMBL1076438 0.79 TSHR (0.64) TSHRTHRBALDH1A1POLBAPEX1
SCHEMBL4526188 0.79 TSHR (0.69) TSHRTHRBALDH1A1POLBAPEX1
SCHEMBL31059270 0.79 TSHR (0.69) TSHRTHRBALDH1A1POLBAPEX1
SCHEMBL13114671 0.78 TSHR (0.57) TSHRTHRBALDH1A1
SCHEMBL1673788 0.77 TSHR (0.67) TSHRTHRBALDH1A1POLBAPEX1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6329125-B2 AN ALKALI-INSOLUBLE COMPOUND HAVING A PROTECTED ALKALI SOLUBLE GROUP IN WHICH PROTECTIVE GROUP CONTAINS AN ALICYCLIC HYDROCARBON GROUP HAVING BONDED TO A CARBON ATOM AND CLEAVED UPON ACTION OF AN ACID GENERATED FROM A PHOTOACID GEENERATOR FUJITSU LIMITED (JP) 2001-12-11 US disclosed
US-20010003640-A1 Chemically amplified resist compositions and process for the formation of resist patterns FUJITSU LIMITED (JP) 2001-06-14 US disclosed
US-6200725-B1 A SUBSTITUTED ALICYCLIC HYDROCARBON GROUP WHICH ACTS AS A PROTECTIVE GROUP TO AN ADDITIONAL POLYMER WHEN EXPOSED TO A POLYACID GENERATOR WHICH IS CAPABLE OF DECOMPOSING TO PATTERN RADIATION EPOSURE, PRODUCES ACID, CAPABLE OF DEPROTECTION FUJITSU LIMITED (JP) 2001-03-13 US disclosed
US-6013416-A FILMS FOR PHOTORESISTS PATTERNS FUJITSU LIMITED (JP) 2000-01-11 US disclosed
US-5968713-A ALKALI DEVELOPED RESISTS AND FILM FORMING COMPOUNDS WITH ALKALI SOLUBLE GROUPS AND GENERATION FUJITSU LIMITED (JP) 1999-10-19 US disclosed