Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TMEM97 | Q5BJF2 | 2/20 | 0.68 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.68 |
| ▸ | MAOB | P27338 | 8/20 | 0.68 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.64 |
| ▸ | MEN1 | O00255 | 3/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.64 |
| ▸ | MAOA | P21397 | 1/20 | 0.59 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.59 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.57 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6302953 | 0.85 | TMEM97 (0.73) | TMEM97SIGMAR1MAOBKDM4EMEN1 | |
| SCHEMBL3075898 | 0.83 | TMEM97 (0.73) | TMEM97SIGMAR1MAOBKDM4EMEN1 | |
| SCHEMBL7741808 | 0.83 | HRH2 (0.57) | KDM4EALDH1A1 | |
| SCHEMBL3075901 | 0.82 | TMEM97 (0.71) | TMEM97SIGMAR1MAOBMEN1KMT2A | |
| SCHEMBL7733935 | 0.82 | KDM4E (0.56) | KDM4EALDH1A1 | |
| SCHEMBL5888854 | 0.82 | TMEM97 (1.00) | TMEM97SIGMAR1MAOBKDM4EMEN1 | |
| SCHEMBL7402131 | 0.81 | TMEM97 (0.82) | TMEM97SIGMAR1MAOBSLC6A2SLC6A4 | |
| SCHEMBL7404295 | 0.81 | TMEM97 (0.82) | TMEM97SIGMAR1MAOBSLC6A2SLC6A4 | |
| Hydrochloric Acid SCHEMBL7402650 | 0.80 | TMEM97 (0.80) | TMEM97SIGMAR1MAOBSLC6A2SLC6A4 | |
| SCHEMBL12607736 | 0.80 | TMEM97 (0.58) | TMEM97SIGMAR1MAOBMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7790744-B2 | Cyclic peptide antifungal agents and process for preparation thereof | ELI LILLY AND COMPANY (US) | 2010-09-07 | — | — | US | disclosed |
| US-7790744-B2 | Cyclic peptide antifungal agents and process for preparation thereof | ELI LILLY AND COMPANY (US) | 2010-09-07 | — | — | US | disclosed |
| US-6743777-B1 | TRISPHENYL ACYL DERIVATIVES OF THE ECHINOCANDIN CLASS; CANDIDA ALBICANS; ANTIFUNGAL AND ANTIPARASITIC; CYCLIC HEXAPEPTIDES HAVING UNIQUE SIDE CHAIN ACYL GROUP | ELI LILLY AND COMPANY | 2004-06-01 | — | — | US | disclosed |
| US-6743777-B1 | TRISPHENYL ACYL DERIVATIVES OF THE ECHINOCANDIN CLASS; CANDIDA ALBICANS; ANTIFUNGAL AND ANTIPARASITIC; CYCLIC HEXAPEPTIDES HAVING UNIQUE SIDE CHAIN ACYL GROUP | ELI LILLY AND COMPANY | 2004-06-01 | — | — | US | disclosed |