Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.45 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.45 |
| ▸ | CLK2 | P49760 | 1/20 | 0.45 |
| ▸ | CSNK1G1 | Q9HCP0 | 1/20 | 0.45 |
| ▸ | CCNC | P24863 | 5/20 | 0.42 |
| ▸ | CDK8 | P49336 | 5/20 | 0.42 |
| ▸ | AXL | P30530 | 1/20 | 0.39 |
| ▸ | CDC7 | O00311 | 8/20 | 0.38 |
| ▸ | GCGR | P47871 | 1/20 | 0.36 |
| ▸ | GSK3B | P49841 | 1/20 | 0.35 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.34 |
| ▸ | CDK2 | P24941 | 1/20 | 0.34 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7690501 | 0.81 | CSNK1A1 (0.58) | CSNK1A1CSNK1DCLK2CSNK1G1CCNC | |
| SCHEMBL31295156 | 0.68 | NAMPT (0.46) | IMPDH2ALDH1A1 | |
| SCHEMBL1889779 | 0.67 | TDP1 (0.46) | CCNCCDK8GSK3BMAPTALDH1A1 | |
| SCHEMBL3812402 | 0.67 | TDP1 (0.59) | CCNCCDK8GSK3BMAPTALDH1A1 | |
| Hydrochloric Acid SCHEMBL641566 | 0.66 | TDP1 (0.58) | CCNCCDK8GSK3BMAPTALDH1A1 | |
| Bromide SCHEMBL5567775 | 0.66 | TDP1 (0.58) | CCNCCDK8GSK3BMAPTALDH1A1 | |
| SCHEMBL7683073 | 0.66 | SMN1; SMN2 (0.51) | CSNK1A1CSNK1DCLK2CSNK1G1AXL | |
| SCHEMBL23204597 | 0.66 | MAP2K1 (0.38) | CSNK1A1CSNK1DCLK2CDK8AXL | |
| SCHEMBL7689328 | 0.66 | CSNK1A1 (0.69) | CSNK1A1CSNK1DCLK2CSNK1G1CCNC | |
| Bromide SCHEMBL9203773 | 0.65 | GSK3B (0.63) | GSK3BMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6417202-B1 | 3-ACETYL-4-METHYL-2,5-DI(4-PYRIDYL)-1H-PYRROLE, FOR EXAMPLE; TREATING CELL ADHESION MOLECULES (CAMS) MEDIATED DISEASES SUCH AS ARTHRITIS, AIDS, SEPTIC SHOCK, CACHEXIA, TRANSPLANT REJECTION | PFIZER INC. | 2002-07-09 | — | — | US | disclosed |