SCHEMBL7742568

SCHEMBL7742568

O=C(O)C1C2C=CCC(C2)C1C(=O)O

nearest known ligand 0.46

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
POLB P06746 5/20 0.46
TDP1 Q9NUW8 3/20 0.46
APEX1 P27695 1/20 0.46
ABAT P80404 1/20 0.38
ALDH1A1 P00352 2/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
MEN1 O00255 1/20 0.36
KMT2A Q03164 1/20 0.36
NPSR1 Q6W5P4 1/20 0.34
TAAR1 Q96RJ0 1/20 0.34
CASP6 P55212 1/20 0.34
CTDSP1 Q9GZU7 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19413967 0.89 POLB (0.41) POLBTDP1APEX1ABATALDH1A1
SCHEMBL26715042 0.84 PPM1B (0.40) POLBABATALDH1A1SMN1; SMN2MEN1
SCHEMBL59471 0.74 POLB (0.70) POLBTDP1APEX1ALDH1A1SMN1; SMN2
SCHEMBL713506 0.74 POLB (0.70) POLBTDP1APEX1ALDH1A1SMN1; SMN2
SCHEMBL14577505 0.74 POLB (0.70) POLBTDP1APEX1ALDH1A1SMN1; SMN2
SCHEMBL23287488 0.74 POLB (0.70) POLBTDP1APEX1ALDH1A1SMN1; SMN2
SCHEMBL20346210 0.74 POLB (0.70) POLBTDP1APEX1ALDH1A1SMN1; SMN2
SCHEMBL381246 0.74 POLB (0.70) POLBTDP1APEX1ALDH1A1SMN1; SMN2
SCHEMBL24062391 0.74 POLB (0.70) POLBTDP1APEX1ALDH1A1SMN1; SMN2
SCHEMBL1462188 0.74 POLB (0.70) POLBTDP1APEX1ALDH1A1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6429270-B2 HIGH ACTIVITY COORDINATION CATALYST OF MAGNESIUM AND TITANIUM, A POLYCARBOXYLIC ACID ESTER, ACID HALIDE ANDORGANOALUMINUM AND ORGANOSILICON COMPOUNDS UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION 2002-08-06 US disclosed
US-20010051697-A1 Off-line preactivated catalysts and prepolymerized catalysts MORSE DAVID BELL (US) 2001-12-13 US disclosed
EP-1115754-A1 OFF-LINE PREACTIVATED CATALYSTS AND PREPOLYMERIZED CATALYSTS UNION CARBIDE CHEMICALS AND PLASTICS COMPANY, INC. (US) 2001-07-18 EP disclosed
WO-2000015673-A1 OFF-LINE PREACTIVATED CATALYSTS AND PREPOLYMERIZED CATALYSTS UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) 2000-03-23 WO disclosed
EP-0291958-A2 Process for producing stereoregular polymers having a narrow molecular weight distribution UNION CARBIDE CORPORATION (US) 1988-11-23 EP disclosed