Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 1/20 | 0.48 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | SIRT1 | Q96EB6 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7743089 | 1.00 | PARP1 (0.48) | PARP1PARP2KDM4ELMNAALOX12 | |
| SCHEMBL5573493 | 0.85 | MAPT (0.45) | PARP1PARP2KDM4ELMNAALOX12 | |
| SCHEMBL5573499 | 0.85 | MAPT (0.45) | PARP1PARP2KDM4ELMNAALOX12 | |
| SCHEMBL5573505 | 0.84 | PARP1 (0.47) | PARP1PARP2KDM4ELMNAALOX12 | |
| SCHEMBL6744695 | 0.82 | MAPT (0.49) | PARP1PARP2KDM4ELMNAALOX12 | |
| SCHEMBL6744700 | 0.82 | MAPT (0.49) | PARP1PARP2KDM4ELMNAALOX12 | |
| Hydrochloric Acid SCHEMBL6744777 | 0.81 | MAPT (0.48) | PARP1PARP2KDM4ELMNAALOX12 | |
| Hydrochloric Acid SCHEMBL6744785 | 0.81 | MAPT (0.48) | PARP1PARP2KDM4ELMNAALOX12 | |
| SCHEMBL13673571 | 0.79 | KDM4E (0.74) | PARP1PARP2KDM4ELMNAALOX12 | |
| SCHEMBL13673568 | 0.79 | KDM4E (0.74) | PARP1PARP2KDM4ELMNAALOX12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001025192-A1 | GUANIDINE DERIVATIVES AND THEIR USE IN THE PRODUCTION OF A MEDICAMENT FOR BLOCKING XANTHINE OXIDASE/DEHYDROGENASE | MELACURE THERAPEUTICS AB (SE) | 2001-04-12 | — | — | WO | disclosed |