SCHEMBL7743244

SCHEMBL7743244

CC(C)(C)OC(=O)N1CCN(Cc2cnc[nH]2)C(Cc2ccc(C#N)cc2)C1

nearest known ligand 0.49

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
GPR119 Q8TDV5 4/20 0.49
FNTA P49354 12/20 0.46
FNTB P49356 12/20 0.46
HRH3 Q9Y5N1 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7743208 0.90 FNTA (0.47) GPR119FNTAFNTBHRH3
SCHEMBL7747657 0.86 FNTA (0.42) GPR119FNTAFNTBHRH3
SCHEMBL7747674 0.85 FNTA (0.45) GPR119FNTAFNTBHRH3
SCHEMBL7162634 0.85 FNTA (0.52) FNTAFNTB
SCHEMBL7743228 0.84 FNTA (0.43) GPR119FNTAFNTBHRH3
SCHEMBL7750454 0.82 FNTA (0.42) GPR119FNTAFNTBHRH3
SCHEMBL7748858 0.81 FNTA (0.41) FNTAFNTBHRH3
SCHEMBL7747665 0.80 FNTA (0.43) FNTAFNTBHRH3
SCHEMBL7747663 0.75 FNTA (0.40) FNTAFNTBHRH3
SCHEMBL7747638 0.75 CYP2D6 (0.41) FNTAFNTBHRH3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2001022963-A1 METHOD OF PREVENTING OSTEOPOROSIS MERCK & CO., INC. (US) 2001-04-05 WO disclosed