SCHEMBL7743558

SCHEMBL7743558

C=CCC=C1CCNC1=O

nearest known ligand 0.35

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
CRBN Q96SW2 1/20 0.35
PARP10 Q53GL7 10/20 0.34
PARP1 P09874 8/20 0.34
PARP11 Q9NR21 6/20 0.34
PDPK1 O15530 1/20 0.34
MAP2K1 Q02750 2/20 0.32
F7 P08709 1/20 0.31
F3 P13726 1/20 0.31
ACHE P22303 1/20 0.31
KDM4E B2RXH2 2/20 0.30
RAF1 P04049 1/20 0.30
MAPK1 P28482 1/20 0.30
MEN1 O00255 1/20 0.30
CYP1A2 P05177 1/20 0.30
HPGD P15428 1/20 0.30
CYP2C19 P33261 1/20 0.30
HTT P42858 1/20 0.30
KMT2A Q03164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL685633 0.74
SCHEMBL240349 0.74
SCHEMBL24569437 0.71 CRBN (0.35) CRBNPARP10PARP1PARP11PDPK1
SCHEMBL28840975 0.71 CRBN (0.35) CRBNPARP10PARP1PARP11PDPK1
SCHEMBL24569427 0.69 CRBN (0.33) CRBNPARP10PARP1PARP11
SCHEMBL24569753 0.69 CRBN (0.33) CRBNPARP10PARP1PARP11
SCHEMBL24569709 0.69 CRBN (0.33) CRBNPARP10PARP1PARP11
SCHEMBL24569850 0.69 CRBN (0.33) CRBNPARP10PARP1PARP11
SCHEMBL28239984 0.68 CCR6 (0.43) CRBNKDM4E
SCHEMBL13065453 0.67

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0868192-A4 FAST DRYING, FILM FORMING IODINE RELEASE SOLUTION ISP INVESTMENTS INC (US) 2001-01-24 EP claimed
EP-0868192-A1 FAST DRYING, FILM FORMING IODINE RELEASE SOLUTION ISP INVESTMENTS INC. (US) 1998-10-07 EP claimed
WO-1997031041-A1 STRONGLY SWELLABLE, MODERATELY CROSS-LINKED COPOLYMERS OF VINYLPYRROLIDONE AND VINYL ACETATE ISP INVESTMENTS INC. (US) 1997-08-28 WO claimed
WO-1997029139-A1 POLYMERIZABLE COMPOSITION OF VINYLPYRROLIDONE AND VINYL CAPROLACTAM ISP INVESTMENTS INC. (US) 1997-08-14 WO claimed
WO-1997013520-A1 FAST DRYING, FILM FORMING IODINE RELEASE SOLUTION ISP INVESTMENTS INC. (US) 1997-04-17 WO claimed
EP-3377034-A1 CROSSLINKED POLYMERS DERIVED FROM MONOMERS HAVING ACRYLOYL AND LACTAM MOIETIES AND SULFONIC ACID/SULFONATE COMONOMERS, COMPOSITIONS THEREOF, AND APPLICATIONS THEREOF Hercules LLC (US) 2018-09-26 EP disclosed
EP-3377549-A1 PROLIFEROUS POLYMERS COMPRISING LACTAMIC MOIETIES ISP Investments LLC (US) 2018-09-26 EP disclosed
EP-3377548-A1 FRAGRANCE DELIVERY COMPOSITION COMPRISING COPOLYMERS OF ACRYLOYL LACTAM AND ALKYLMETHACRYLATES, PROCESS FOR PREPARING THE SAME, AND METHOD OF USE THEREOF ISP Investments LLC (US) 2018-09-26 EP disclosed
EP-0868192-A4 FAST DRYING, FILM FORMING IODINE RELEASE SOLUTION ISP INVESTMENTS INC (US) 2001-01-24 EP disclosed
EP-0868192-A1 FAST DRYING, FILM FORMING IODINE RELEASE SOLUTION ISP INVESTMENTS INC. (US) 1998-10-07 EP disclosed
WO-1997031041-A1 STRONGLY SWELLABLE, MODERATELY CROSS-LINKED COPOLYMERS OF VINYLPYRROLIDONE AND VINYL ACETATE ISP INVESTMENTS INC. (US) 1997-08-28 WO disclosed
WO-1997029139-A1 POLYMERIZABLE COMPOSITION OF VINYLPYRROLIDONE AND VINYL CAPROLACTAM ISP INVESTMENTS INC. (US) 1997-08-14 WO disclosed
WO-1997013520-A1 FAST DRYING, FILM FORMING IODINE RELEASE SOLUTION ISP INVESTMENTS INC. (US) 1997-04-17 WO disclosed
EP-0687250-A4 1996-01-10 EP disclosed
EP-0687250-A1 1-VINYL-3(E)-ETHYLIDENE PYRROLIDONE ISP INVESTMENTS INC. (US) 1995-12-20 EP disclosed
EP-0625994-A4 PURIFICATION OF VINYL LACTAM POLYMERS. ISP INVESTMENTS INC (US) 1995-10-04 EP disclosed
EP-0625994-A1 PURIFICATION OF VINYL LACTAM POLYMERS ISP INVESTMENTS INC. (US) 1994-11-30 EP disclosed
WO-1994020461-A1 1-VINYL-3(E)-ETHYLIDENE PYRROLIDONE ISP INVESTMENTS INC. (US) 1994-09-15 WO disclosed
WO-1993016114-A1 PURIFICATION OF VINYL LACTAM POLYMERS ISP INVESTMENTS INC. (US) 1993-08-19 WO disclosed