Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 18/20 | 0.56 |
| ▸ | BRS3 | P32247 | 1/20 | 0.46 |
| ▸ | CALCRL | Q16602 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7745563 | 0.95 | TACR1 (0.56) | TACR1BRS3 | |
| SCHEMBL7737642 | 0.92 | TACR1 (0.54) | TACR1BRS3CALCRL | |
| SCHEMBL7743822 | 0.92 | TACR1 (0.58) | TACR1BRS3 | |
| SCHEMBL7743510 | 0.91 | TACR1 (0.60) | TACR1BRS3CALCRL | |
| SCHEMBL7742314 | 0.89 | TACR1 (0.60) | TACR1BRS3CALCRL | |
| SCHEMBL7743755 | 0.88 | TACR1 (0.60) | TACR1BRS3CALCRL | |
| SCHEMBL7743608 | 0.88 | TACR1 (0.65) | TACR1BRS3CALCRL | |
| SCHEMBL7743527 | 0.87 | TACR1 (0.65) | TACR1BRS3CALCRL | |
| SCHEMBL7745573 | 0.86 | TACR1 (0.54) | TACR1BRS3 | |
| SCHEMBL7743176 | 0.86 | TACR1 (0.64) | TACR1BRS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0819005-A4 | 2-ACYLAMINOPROPANAMIDES AS TACHYKININ RECEPTOR ANTAGONISTS | LILLY CO ELI (US) | 2001-03-21 | — | — | EP | disclosed |
| EP-0819005-A1 | 2-ACYLAMINOPROPANAMIDES AS TACHYKININ RECEPTOR ANTAGONISTS | ELI LILLY AND COMPANY (US) | 1998-01-21 | — | — | EP | disclosed |
| EP-0761220-A1 | 2-Acylaminopropanamides as growth hormone secretagogues | ELI LILLY AND COMPANY (US) | 1997-03-12 | — | — | EP | disclosed |
| WO-1997006803-A1 | 2-ACYLAMINOPROPANAMIDES AS GROWTH HORMONE SECRETAGOGUES | ELI LILLY AND COMPANY (US) | 1997-02-27 | — | — | WO | disclosed |
| US-5565568-A | USEFUL IN TREATMENT OR PREVENTION OF A PHYSIOLOGICAL DISORDER ASSOCIATED WITH AN EXCESS OF TACHYKININS | ELI LILLY AND COMPANY (US) | 1996-10-15 | — | — | US | disclosed |
| WO-1996031214-A1 | 2-ACYLAMINOPROPANAMIDES AS TACHYKININ RECEPTOR ANTAGONISTS | ELI LILLY AND COMPANY (US) | 1996-10-10 | — | — | WO | disclosed |