Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 2/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
| ▸ | GPR84 | Q9NQS5 | 4/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7743672 | 0.89 | ACE2 (0.44) | LMNAACE2OPRM1SPHK1MEN1 | |
| SCHEMBL7743761 | 0.89 | ACE2 (0.44) | LMNAACE2OPRM1SPHK1MEN1 | |
| SCHEMBL7744228 | 0.85 | ACE2 (0.40) | LMNAACE2PTPN1MEN1ALOX15 | |
| SCHEMBL7744252 | 0.81 | ACE2 (0.38) | LMNAACE2OPRM1CA1SPHK1 | |
| SCHEMBL7743773 | 0.81 | TSHR (0.38) | LMNAACE2PTPN1MEN1ALOX15 | |
| SCHEMBL31166041 | 0.81 | AKR1B1 (0.53) | LMNAPTPN1MEN1ALOX15KMT2A | |
| SCHEMBL7743686 | 0.80 | FFAR4 (0.42) | LMNAACE2OPRM1SPHK1MEN1 | |
| SCHEMBL7743492 | 0.80 | FFAR4 (0.42) | LMNAACE2OPRM1SPHK1MEN1 | |
| SCHEMBL5605814 | 0.80 | ACE2 (0.42) | LMNAACE2OPRM1CA1SPHK1 | |
| SCHEMBL7743524 | 0.80 | ACE2 (0.42) | LMNAACE2OPRM1CA1SPHK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001002512-A1 | USE OF DIMERIZED FISCHER-TROPSCH PROCESS PRODUCTS AND VINYLIDENE DERIVATIVES THEREOF | SASOL TECHNOLOGY (PTY) LTD. (ZA) | 2001-01-11 | — | — | WO | disclosed |